Author(s):
Anikumar Aher, Sonali Gawali, Chetan Darade, Pranjal Jadhav, Vaishnavi Kamble, Suraj Kharat, Harshada Tamkhane, Vaibhav Pawar
Email(s):
daradechetan1999@gmail.com
DOI:
10.52711/2231-5675.2025.00017 
Address:
Anikumar Aher, Sonali Gawali, Chetan Darade*, Pranjal Jadhav, Vaishnavi Kamble, Suraj Kharat, Harshada Tamkhane, Vaibhav Pawar
1Department of Pharmacognosy, MVPs College of Pharmacy, Nashik 422002, Maharashtra, India.
*Corresponding Author
Published In:
Volume - 15,
Issue - 2,
Year - 2025
ABSTRACT:
Phytochemical and toxicological studies was evaluated by Methanol extract of Agave sisalana. The sisal leaf consist of alkaloids, saponins, flavonoids and some cardiac glycosides. Sisal is a primary source of hard fiber of Agave sisalana. The plant leaf is exploited in ayurvedic medicine for the treatment of antimicrobial infections such as Bacterial conjunctivitis, scabies and skin reactions due to the microbial. The sisal portions are extracted separately by reflux at least 12hrs by with the help of HCL solution and methanol to provide the crude sisal residue extract respectively. The study involving in the extract's phytochemical composition (flavonoids) and evaluating comparative properties like Hemotoxicity as well as cytotoxicity, sometimes the antioxidant and antiglycation activities of the plant extract and cream-gel are evaluated, sisal composed of Catechin and Kaempferol. Sisal extract and its formulations are demonstrated for proven antioxidant and antiglycation property. The cream-gel's having UVB and UVA protection and very good effectiveness with the HER and it was match same that of synthetic UVB/UVA sunscreen protectants. Significantly it was concluded that the presence of flavonoids and alkaloids in the extract. The plant leaf is having moderate toxicological contains and it could be used in herbal formulations for therapeutic uses. The pesticidal and insecticidal response of extract from the plant is reported. Antimicrobial activity of sisal extracts leaves and leaf marc carried out to evaluate and discarded in the process of obtaining the hard fibers.
Cite this article:
Anikumar Aher, Sonali Gawali, Chetan Darade, Pranjal Jadhav, Vaishnavi Kamble, Suraj Kharat, Harshada Tamkhane, Vaibhav Pawar. Characterization and Investigation Study on Agave sisalana Perrine. Asian Journal of Pharmaceutical Analysis. 2025; 15(2):103-8. doi: 10.52711/2231-5675.2025.00017
Cite(Electronic):
Anikumar Aher, Sonali Gawali, Chetan Darade, Pranjal Jadhav, Vaishnavi Kamble, Suraj Kharat, Harshada Tamkhane, Vaibhav Pawar. Characterization and Investigation Study on Agave sisalana Perrine. Asian Journal of Pharmaceutical Analysis. 2025; 15(2):103-8. doi: 10.52711/2231-5675.2025.00017 Available on: https://ajpaonline.com/AbstractView.aspx?PID=2025-15-2-6
REFERENCE:
1. FAO (2009). Role of forestry in combating desertification. FAO Corporate document repository, Rome Italy. Gentry HS (2004).
2. Paperback edition. Agaves of Continental North America. University of Arizona press, USA.
3. Ghule BV, Murugananthan G, Yeole PG. Analgesic and antipyretic effects of Capparis zeylanica leaves. Fitoterapiam. 2007; 78: 365-369.
4. Phiri IK, Phiri AM, Ziela M, Chota A, Masuku M, Monrad J. Prevalence and distribution of gastrointestinal helminthes and their effects on weight gain in free-range chickens in Central Zambia. Trop. Anim. Health Prod. 2007; 39: 309-315.
5. Popov SV, Popova GY, Ovodova RG, Ovodov YS. Antiinflammatory activity of the pectic polysaccharide from Comarum palustre. Fitoterapia. 2005; 76: 281-287.
6. Study of the medicinal plants International Journal of Bioassays Ngule, C.M., Swamy, A. Phytochemical and bioactivity evaluation of Senna didymobotrya Fresen Irwin used by the Nandi community in Kenya. International Journal of Bioassays. 2013; 2: 1037–1043.
7. Ong, H.G., Kim, Y.D. Quantitative ethnobotanical study of the medicinal plants used by the Ati Negrito indigenous group in Guimaras island, Philippines. Journal of Ethnopharmacology. 2014; 157: 228–242.
8. Phillips, O., Gentry, A.H. The useful plants of Tambopata, Peru: I. Statistical hypotheses tests with a new quantitative technique. 1993.
9. Cytotoxicity and oral acute toxicity studies of Lantana camara leaf extract. Molecules. 2002; 16: 3663–3674.
10. Radebe, F., De Gita, G., Ndlovu, M., Vezi, A., Kekana, V., Maseko, V., Takuva, S. Microbiological surveillance of sexually transmitted infections in Johannesburg, Gauteng Province. Communicable Diseases Surveillance Bulletin. 2013; 12: 108–111.
11. Radwan, M.M., Badawy, A., Zayed, R., Hassanin, H., ElSohly, M.A., Ahmed, S.A. Cytotoxic flavone glycosides from Solanum elaeagnifolium. Medicinal Chemistry Research. 2015; 24: 1326–1330.
12. Ramulondi, M. Toxicology and Herb-Drug Interaction of Selected Anti-Hypertension Plants Used by Lay Persons in Northern KwaZulu-Natal (South Africa). Masters’ dissertation. University of Zululand, Richards Bay. 2017
13. Saha A, Masud MA, Bachar SC, Kundu JK, Datta BK, Nahar, L, Sarker SD. The analgesic and anti-inflammatory activities of the extracts of Phyllanthus reticulates in Mice Model. Pharmaceut. Biol. 2007; 45(5): 355-359.
14. Statistical Analytical Systems (SAS). SAS/STAT Release 8.1 Edition SAS Institute Inc, Cary, North Carolina, USA. 2004
15. Sawadogo WR, Boly R, Lompo M, Some N, Lamien CE, Guissou IP, Nacoulma OG. Anti-inflammatory, analgesic and antipyretic activites of Dicliptera verticillata. Int. J. Pharmacol. 2006; 2(4): 435-438.
16. van Wyk B-E, Gericke N (2003). People’s plants: A guide to useful plants of Southern Africa, (1st Edition, 2nd Impression), Briza Publications, Pretoria, pp. 298-299.
17. Rodriguez P, Strong MT. Monocots and Gymnosperms of Puerto Rico and the Virgin Islands. Contributions from the United States National Herbarium. 2005; 52: 1-416.
18. A. F, Hammuel C, Ezeayanaso C, Ogabiela E. E, Udiba U. U, Anyim B. and Olabanji O. Preliminary phytochemical and antimicrobial screening of Agave sisalana Perrine juice (waste) Journal of Environmental Chemistry and Ecotoxicology. 2011; 3(7): 180-183.
19. Gol Available http://www.academicjournals.org/jece 2141-226X ©2011 Academic Journals.
20. Amadioha AC. Controlling rice blast In vitro and In vivo with extracts of Azadirachta indica. Crop Prot. 2000; 19(5): 287-290.
21. Anwar A, Bhat GN, Singhara GN. Management of sheath blight and blast in rice through seed treatment. Ann. Pl. Protec. Sci. 2002; 10: 285-287.
22. Awodera V A and Esuruoso O F. Reduction in grain yield of two rice varieties infected by rice blast disease in Nigeria. Nigerian Agric J. 1975; 11:170-3.
23. Babar LK, Iftikhar T, Khan HN, Hameed MA. Agronomic trials on sugarcane crop under Faisalabad conditions, Pakistan. Pak. J. Bot. 2011; 43(2): 929-935.
24. Bandeira and Silva, D.A. Bandeira, O.R.R.F. Silva Aproveitamento de residuos W. Andrade (Ed.), O sisal do Brasil, Sindifibras, Salvador. 2006: 56-61.
25. Debnath M, Pandey M, Sharma R, Thakur G. S, Lal P. Biotechnological intervention of Agave sisalana a unique fiber yielding plant with medicinal Property. J. Med. Plants Res. 2010; 43: 177-187.
26. FAO. Food and Agriculture Organization of the United Nations. Animal Feed Resources Information System. Food and Agriculture Organization of the United Nations. Animal Feed Resources Information. 2012.
27. Gohel NM, Chauhan HL, Mehta AN. Bio-efficacy of fungicides against Pyricularia oryzae the incitant of rice blast. J. Plant Dis. Sci. 2008; 3(2): 189-192.
28. Iftikhar T, Babar LK, Zahoor S, Khan NG. Best Irrigation Management Practices in Cotton. Pak. J. Bot. 2010; 42(5): 3023-3028.
29. Jia Y, McAdams SA, Bryan GT, Hershey HP, Valent B. Direct interaction of resistance gene and avirulence gene products confers rice blast resistance. The EMBO Journal. 2000; 19(15): 4004-4014.
30. Judith Hubert, Robert B, Mabagala, Delphina P. Mamiro. Efficacy of Selected Plant Extracts against Pyricularia grisea, Causal Agent of Rice Blast Disease. American Journal of Plant Sciences. 2015; 6:, 602-611 Article published 12 March 2015.2011. Under Bot.,
31. MAFF. Rice-epidemic region and yield loss., Statistics and Information Department (eds.), The Ministry of Agriculture, Forestry and Fisheries of Japan (MAFF), Tokyo. Silva (Ed.), 2006). 2007 Commonwealth Mycological Institute, ISBN 0 85198 545 9.of the Feed stem.
32. Ribot C, Hirsch J, Balzergue S, Tharreau D, Notteghem JH,. Lebrun MH, Morel JB. Susceptibility of rice to the blast fungus, Magnaporthe grisea. J. Plant Physiol. 2008; 165: 114-24.
33. PROTA, 2012. PROTA 4U web database. Plant resources of Tropical Africa. PROTA. http://www.prota4u.
34. LP. Marma, MJ. Potgieter, A. Samie, Ithnobotanical survey of inmasive alien plant species used in thetreatment of smally transmitted infections as Wonerberg District, South Africa South Afr. J. Bot. 2019
35. Vans, A. Batu 1. Parwich. A preliamsary dassation of the heading part of ne parts, have on a national aules of an ethanol. Economic Botany. 2011; 47: 15–32.