Volume No. :   9

Issue No. :  2

Year :  2019

ISSN Print :  2231-5667

ISSN Online :  2231-5675


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Forced Degradation Study for Tolterodine by HPLC with PDA Detection

Address:   Tentu Nageswara Rao1*, Imad Hussain1, Y. Prashanthi2, T. B. Patrudu3
1School of Materials Science and Engineering, Changwon National University, Changwon, Gyeongnam, 641-773, Republic of Korea.
2Department of Chemistry, Mahatma Gandhi University, Nalgonda, Telangana, India
3Department of Chemistry, Gitam University, Hyderabad Campus, Telangana, India.
*Corresponding Author
DOI No: 10.5958/2231-5675.2019.00015.2

A simple and inexpensive method was developed with high performance liquid chromatography with PDA detection for determination of Tolterodine. The chromatographic separations were achieved on (250×4.6 mm), 5.0 µm make: X-terra C18 column employing Acetonitrile: 0.1% v/v phosphoric acid in Water (35:65, v/v) as mobile phase with gradient programmed at flow rate 1.0 mL/min was chosen. The detector wavelength of 210 nm was employed.
Forced degradation, HPLC, Method validation, Tolterodine.
Tentu Nageswara Rao, Imad Hussain, Y. Prashanthi, T. B. Patrudu. Forced Degradation Study for Tolterodine by HPLC with PDA Detection. Asian J. Pharm. Ana. 2019; 9(2):77-81.
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