Author(s):
Gurappa Kashinath Dyade, Shyam Pralhad Bothikar, Bandu Eknath Zarekar, Dipali Bhimdevrao Taware
Email(s):
gkdyade@gmail.com
DOI:
10.52711/2231-5675.2026.00040 
Address:
Gurappa Kashinath Dyade1*, Shyam Pralhad Bothikar2, Bandu Eknath Zarekar3, Dipali Bhimdevrao Taware4
1Dept of Postgraduate in Pharmaceutical Quality Assurance, SVPM’S College of Pharmacy, Malegaon (BKII), Baramati Dist Pune - 413115, Maharashtra, India.
2Board of Managemant, Cure Medicines India Pvt Ltd, MIDC Bhosari - 411026, Pune, Maharashtra, India.
3R and D Department, Glenmark Research Centre, Taloja, Navi Mumbai, Maharashtra - 410208, India.
4SVPM’S College of Pharmacy, Malegaon (BKII), Baramati Dist Pune - 413115, Maharashtra, India.
*Corresponding Author
Published In:
Volume - 16,
Issue - 4,
Year - 2026
ABSTRACT:
Objective: An improved reverse phase high-performance liquid chromatographic (RP-HPLC) method has been developed and validated for the estimation of Favipiravir from pharmaceutical dosage form. Method: Chromatographic separation was performed on RP-C18 column. The optimized mobile phase (acetonitrile: water of pH 4.8 adjusted with glacial acetic acid) was pumped at a flow rate of 0.8ml/min in the ratio of 35:65% v/ v and the eluent was monitored at 245nm. Results: The assay was performed with tablet dosage form and % of assay was found 101.21% w/w of Favipravir. Linearity was ascertained over the concentration range 1-12µg/ml. The method was statistically validated and found SD; RSD was within acceptable limit, indicated high degree of accuracy and precision of the proposed RP-HPLC method. Conclusion: Due to its simplicity, rapidness, high precision and accuracy the proposed RP-HPLC method can be applied for determination of Favipiravir in routine quality control tests of dosage form.
Cite this article:
Gurappa Kashinath Dyade, Shyam Pralhad Bothikar, Bandu Eknath Zarekar, Dipali Bhimdevrao Taware. New Improved RP-HPLC Method for The Estimation of Favipiravir from Solid Dosage Form. Asian Journal of Pharmaceutical Analysis. 2026; 16(4):259-4. doi: 10.52711/2231-5675.2026.00040
Cite(Electronic):
Gurappa Kashinath Dyade, Shyam Pralhad Bothikar, Bandu Eknath Zarekar, Dipali Bhimdevrao Taware. New Improved RP-HPLC Method for The Estimation of Favipiravir from Solid Dosage Form. Asian Journal of Pharmaceutical Analysis. 2026; 16(4):259-4. doi: 10.52711/2231-5675.2026.00040 Available on: https://ajpaonline.com/AbstractView.aspx?PID=2026-16-4-2
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