Author(s): Pallavi Suthar, Rajshree Mashru

Email(s): pallaveemali12@gmail.com , rajshreemashru@yahoo.com

DOI: 10.52711/2231-5675.2024.00001   

Address: Pallavi Suthar1*, Rajshree Mashru2
1Assistant Professor, Shree Swaminarayan Sanskar Pharmacy Collage, Zundal, Gujarat.
2 Professor, The Maharaja Sayajirao University of Baroda, Vadodara, Gujart.
*Corresponding Author

Published In:   Volume - 14,      Issue - 1,     Year - 2024


ABSTRACT:
In the proposed research paper, a simple and accurate colorimetric method has been developed for the estimation of Azelnidipine in bulk. Instead of a traditional UV spectrophotometer, the proposed method measures the colour intensity of a solution using a smartphone camera and an application. This colorimetric method was found to be linear in the concentration range of 2µg/ml to 10µg/ml with an r2 value of 0.9993. The limits of detection (LOD) and quantification (LOQ) were found to be 0.024µg/ml and 0.068µg/ml, respectively.


Cite this article:
Pallavi Suthar, Rajshree Mashru. Simple Colourimetric Method and Development of A Colour Kit for on-the-spot Azelnidipine Estimation using A Smartphone Application, with Comparison to the UV-Spectroscopic Method. Asian Journal of Pharmaceutical Analysis. 2024; 14(1):1-5. doi: 10.52711/2231-5675.2024.00001

Cite(Electronic):
Pallavi Suthar, Rajshree Mashru. Simple Colourimetric Method and Development of A Colour Kit for on-the-spot Azelnidipine Estimation using A Smartphone Application, with Comparison to the UV-Spectroscopic Method. Asian Journal of Pharmaceutical Analysis. 2024; 14(1):1-5. doi: 10.52711/2231-5675.2024.00001   Available on: https://ajpaonline.com/AbstractView.aspx?PID=2024-14-1-1


REFERENCES:
1.    https://pubchem.ncbi.nlm.nih.gov/compound/Azelnidipine
2.    Rele RV, Patil SP. Ultra-Violet Spectrophotometric Method for Estimation of Azelnidipine from Bulk Drug and Pharmaceutical Formulation. Asian Journal of Research in Chemistry. 2010; 3(4): 1077-9
3.    Mandale D, Mistry R, Chauhan N. An analytical approach of azelnidipine: a review. Muralidharan S, S. Parasuraman and V. Venugopal, Simple Validation of Azelnidipine By RP-HPLC Method. Rapports De Pharmacie. 2015; 1(1): 43-45.
4.    Raskapur KD, Patel MM, Captain AD. UV-Spectrophotometric method development and validation for determination of Azelnidipine in pharmaceutical dosage form. Toxicology. 2010; 106: 135-43.
5.    Shewale VU, et al. Azelnidipine: A Review on Therapeutic Role in Hypertension. Journal of Drug Delivery and Therapeutics. 2019; 9: 1002-1005.
6.    Mellon MG. The Role of Spectrophotometry in Colorimetry. Industrial and Engineering Chemistry Analytical Edition. 1937; 9(2): 51-6. https://doi.org/10.1021/ac50106a001
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8.    S. Yuvasri, S. Murugan and T. Vetrichelvan. FIRST- Order Derivative and UV-Spectrophotometric Methods For Simultaneous Determination Of Telmisartan And Azelnidipine In Bulk And Tablet Dosage Form. European Journal of Biomedical and Pharmaceutical Science.  2021; 8(5): 290-294.
9.    Bhati KN, Mashru R. Development and Validation of Extractive Spectrophotometric Method for Estimation of Hydroxychloroquine Sulphate by using Smartphone Application. Journal of Drug Delivery and Therapeutics. 2022; 12(3): 49-56 DOI: http://dx.doi.org/10.22270/jddt.v12i3.5460
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