Author(s): Amitkumar J. Vyas, Shalini Anilkumar Jha, A.B. Patel, AI Patel, S. R. Shah, D. B. Sheth

Email(s): amitvyas77@gmail.com , shalinijha925@gmail.com , abp2038@gmail.com , aipvk84@gmail.com , sunnyrshah@gmail.com , devanghsheth@gmail.com

DOI: 10.52711/2231-5675.2022.00026   

Address: Amitkumar J. Vyas, Shalini Anilkumar Jha, A.B. Patel, AI Patel, S. R. Shah, D. B. Sheth
B.K. Mody Government Pharmacy College, Rajkot, Gujarat, India.
L. M. College of Pharmacy, Ahmedabad, Gujarat, India.
*Corresponding Author

Published In:   Volume - 12,      Issue - 2,     Year - 2022


ABSTRACT:
The article consists of brief review on Simultaneous equation method (Vierodt’s method). This method is applicable for estimation of those drugs whose spectra overlap properly I.e. If a sample contains two absorbing drug each of which absorbing at ?max of the other, it is possible to determine both drugs by technique of simultaneous equation method. This article consists of the list of various combined dosage form and food sample analyzed by Vierodt’s method with its wavelength, linearity range and choice of solvents. This method permits simple, rapid and direct determination of combined dosage form without prior separation and therefore can be used in routine analysis. Quantitative estimation is necessary before introduction of any drug into the market because if concentration is more in formulation it can lead to toxicity problem or if concentration is found less, then formulation will not be effective in prescribed dose.


Cite this article:
Amitkumar J. Vyas, Shalini Anilkumar Jha, A.B. Patel, AI Patel, S. R. Shah, D. B. Sheth. Review on Simultaneous Equation Method (Vierodt’s Method). Asian Journal of Pharmaceutical Analysis. 2022; 12(2):149-6. doi: 10.52711/2231-5675.2022.00026

Cite(Electronic):
Amitkumar J. Vyas, Shalini Anilkumar Jha, A.B. Patel, AI Patel, S. R. Shah, D. B. Sheth. Review on Simultaneous Equation Method (Vierodt’s Method). Asian Journal of Pharmaceutical Analysis. 2022; 12(2):149-6. doi: 10.52711/2231-5675.2022.00026   Available on: https://ajpaonline.com/AbstractView.aspx?PID=2022-12-2-14


REFERENCES:
1.    Saini V and Chaudhary J, A. Simultaneous estimation of multicomponent formulations by UV visible Spectroscopy: An Overview. International Research Journal of Pharmacy. 2011,81
2.    Beckatt A.H and Stenlake J.B. Practical Pharmaceutical Chemistry. Fourth Edition, CBS Publisher and Distributor; New Delhi. 2005, 284-286.
3.    Nagulwar VP and Bhusari P. Development of UV-Spectrophotometric Vierordt’s Method for the Simultaneous Estimation of Abacavir and Lamivudine in Combine Dosage form. Scholar Research Library. 2012,728-733.
4.    Thummala K and Gupta M. Estimation of Ledipasvir and Sofosbuvir by Vierordt’s Method in bulk and Dosage Form. International Journal of Pharmacy and Biological Science. 2015, 35-41
5.    EL-Lieth S and Abdul Rashid S. Validation and application of Vierordt’s Method Spectrophotometric method for simultaneous estimation of Tamoxifen/Co-enzyme Q10 in their binary mixture and pharmaceutical dosage forms. ELSEVIER. 2016,319-325.
6.    Vishwal T.S, et all. Simultaneous estimation of Atorvastatin and Clopidogrel by Simultaneous Equation Method in Capsule Dosage Form. IJPSR. 2019, 3305-3310.
7.    Swapna P.V, et al. Analytical method development and validation for simultaneous estimation of Propranolol hydrochloride and Etizolam in their combined dosage form by Vierordt’s Method. IJBCS. 2014 ,46-50.
8.    Sabarwal N, et al. Spectrometric method for simultaneous determination of Amiloride and Hydrochlorothiazide in combined dosage forms. Journal of Advanced Scientific Research .2021, 170-74.
9.    Sharma M, et al. Development and validation of Vierordt’s method for simultaneous estimation of Aspirin and Omeprazole in their combined binary dosage form. Advanced Journal of Chemistry .2020, 328-336.
10.    Sarmila D, et al. Development and validation of Vierordt’s method for simultaneous estimation of Canaglifloxin and Metformin hydrochloride in their combined binary dosage form. International Journal of Pharmaceutical Chemistry and Analysis .2018, 94-99.
11.    Patel A, et al. Development and validation of Vierordt’s method for simultaneous estimation of Dapaglifloxin and Saxagliptin in their combined binary dosage form. Journal of Medical Pharmaceutical and Allied Science . 2000, 2536-2543.
12.    Chavan RR, et al. Development and validation of Vierord’s method for simultaneous estimation of Furosemide and Spironolactone in their combined binary dosage form. 2018, 74-90.
13.    Padmaja N and Veera G. Development and validation of Vierordt’s method for simultaneous estimation of Empagliflozin and Linagliptin in their combined binary dosage form. Scholar Research Library .2015, 306-312.
14.    Patel PB. Development and validation of a method for simultaneous estimation of ofloxacin and ornidazole in different dissolution media. Pharm Methods. 2012,102-5.
15.    Sharma R, et al. Spectrometric method for simultaneous determination of Paracetamol and Diclofenac in combined dosage forms by Vierordt’s method. Journal of Pharmaceuticals Science and Research. 2010, 821-826.
16.    Giriraj P and Sivakkumar T. Development and validation of Vierordt’s method for simultaneous estimation of Paracetamol and Flupirtine Maleate in their combined binary dosage form. Hindawi. 2014,1-6.
17.    Shetty R and Patil D. Application of Simultaneous Equation Method of Rabeprazole Sodium and Levosulpride in Pharmaceutical dosage form. Journal of Association of Arab University for Basic and Application Science. 2014, 53-60.
18.    Chitlange S, et al. Simultaneous estimation of Diacerin and Accelofenac in tablet dosage form. Scholar Research Library. 2010,335-341.
19.    Kumar s and Ramesh G. Simultaneous estimation of Sitagliptin and Pioglitazone by UV-Spectroscopic Method and Study of Interference of Various Excipients on This Combination of Drug. International Journal of Current Pharmaceuticals Research. 2012, 113-116.
20.    Rawat S and Gupta A. Spectrophotometric Method for Simultaneous Estimation of Nimesulide and Diclofenac Sodium in Pharmaceutical Dosage Form. Asian Pharma Press .2011,85-87.
21.    Atole D and Rajput H. Ultraviolet Spectroscopy and its Application - A Brief Review Asian Journal of Pharmaceutical and Clinical Research. 2018,59-66.
22.    Pant M, et al. Application of UV spectrophotometric methods for simultaneous estimation of norfloxacin and tinidazole in bulk and tablet dosage forms. Pharm Chem .2012,4, 6-1041.
23.    Suvagya V, et al. Simultaneous Estimation of Rabeprazole Sodium and Cinitapride Hydrogen Tartrate in Combined pharmaceutical Formulation. Indian Journal of Pharmaceuticals Science and Research. 2013,1868-1873.
24.    Fanse S and Rajput S. Method Development and Validation for Simultaneous Estimation of Aspirin and Lansoprazole in Bulk and Laboratory Sample by Different UV Spectrophotometric Technique. Indian Journal of Pharmaceutical Science and Research .2015,3534-3543.
25.    Mundhey D,et al. Simultaneous Quantification of Buprenorphine Hydrochloride and Naloxone hydrochloride by Vierordt’s Method. International Journal of Science and Pharmaceutical Science .2016, 101-107.
26.    Patel A, et al. Simultaneous estimation of cefepime hydrochloride and sulbactam sodium in combined dosage form. Journal of Chemical and pharmaceutical Research .2015,866-865
27.    Sharma M, et al. Development and Validation of Vierordt’s and Absorbance Ratio Spectrophotometric Methods for Simultaneous Estimation of Aspirin and Omeprazole in Their Binary Mixture. Advanced Journal of Chemistry. 2020,328-335.
28.    Malhotra D and Kalia A. Spectrometric method for simultaneous determination of Azithromycin and Prednisolone in combined dosage forms by Vierordt’s method. International Journal of Pharmacy and pharmaceutical Science .2011,299-302.
29.    Kubal S and Kudchalkar S. Simultaneous Equation Method for The Estimation of Cefpodoxime Proxetil and Levofloxacin Hemihydrate in their Combined Tablet Dosage Form by UV-Visible Spectrophotometry.World Journal of Pharmacy and pharmaceutical Science .2016,1460-1472.
30.    Sheikh F, et al. Simultaneous Equation Method for The Estimation of Clinidipine and Telmisartan in their Combined Tablet Dosage Form by UV-Visible Spectrophotometry. World Journal of Pharmacy and pharmaceutical Science .2020,913-921.
31.    Damle M.c, et al. Spectrometric method for simultaneous determination of Domperidone and Illaprazole in combined dosage forms by Vierordt’s method. Journal of Pharmacy Science Biological Scientific Research. 2018,1 44-147.
32.    Rizk M, et al. Applicability of Bivariate Calibration Alogorithm and Vierord’s Method for Simultaneous estimation of Timolol Maleate and Brimonidine Tartarate in their Binary Mixture.International Journal of pharmaceutical Science and Research .2014, 2631-2641.
33.    Rathee P, et al. Stability Indicating UV-Spectroscopic for Simultaneous determination of Losartan Pottassioum and Hydrochlorthiazide. EJAC .2009, 98-109.
34.    Panchale W, et al. Simultaneous estimation of salbutamol sulphate and ambroxol HCl from their combined dosage form by UV-VIS spectroscopy using simultaneous equation method. GSC biological and pharmaceutical Science.2020, 127-134.
35.    Vyas A, et al. Simultaneous estimation of Nabumetone and Paracetamol in their combined dosage form by Vierordt’s Method. International Journal of Chem Tech Research .2010,543-547.
36.    Shrikkrishna B, et al. Simultaneous Estimation of Ebastine and Monteleukast Sodium.International Journal of Advances in pharmaceutical Science.2014, 1817-1820.
37.    Atul A, et al. Development and Validation of UV Spectrophotometric Method for Simultaneous Estimation of Quinfamide and Mebendazole in in-house Pharmaceutical Formulation. Journal of Pharmaceutical Technology, Research and Management.2018, 10-19.
38.    Sen A and Hinsu D. Analytical method Development and Validation of Tenegliptin Hydrobromide hydrate and Metformin. Journal of Applied pharmaceutical Science. 2016, 157-165.
39.    Masthannamma S. k, et al. Simultaneous Equation Method and Absorption Correction Method for the Estimation of Perindropril Erbumine and Amlodipine Besylate in Bulk and in Combined Tablet Dosage Form Using UV-Spectrophotometer.International Journal of pharmaceutical Science and Research. 2015, 2484-2490.
40.    Sayeed K, et al. Stability Indicating UV-Spectroscopic for Simultaneous determination of Tamsulosin and Dutasteride in Bulk Drugs and pharmaceutical Dosage Forms Using UV-Spectrophotometric Method. International Journal of Research and Development in Pharmacy and Life Sciences. 2015 ,2278-2238.
41.    Rathee P, et al. Stability Indicating UV-Spectroscopic for Simultaneous determination of Losartan Pottassioum and Hydrochlorthiazide. EJAC .2009,98-109.
42.    Khedekar P.B, et al. Application of Vierordt’s for estimation of Rosiglitazone Maleate and Glimperide in Tablet. Digest Journal of Nanomaterial and biostructure. 2009,739-746.
43.    Rebwar O, et al. Simultaneous Spectrophotometric Determination of Thiamine and Pyridoxine in Multivitamin Dosage Forms using H-point Standardization and Vierordt’s Method. Journal of Iranian Chemical Society .1603-1612.
44.    DangeY.D, , et al .Simultaneous Equation Method for Estimation of Palbociclib and Letrozole by UV-Visible Spectrometry. Indian Drugs. 2016 ,61-66.
45.    Alagar M ,et al. Spectrophotometric(Vierordt’s Method) for simultaneous estimation of Episone Hydrochloride and Dicolfenac Sodium in Rapisone-D SR capsules. Research Article. 2013, 683-686
46.    Katiravan P, et al. Development and Validation of a Spectrophotometric method using Vierordt’s method for simultaneous estimation of Moxifloxacin and Cefixime in tablet Formulation. Intercontinental Journal of Pharmaceutical Investigation and Research. 2014,16-22
47.    Bhaskar L ,et al . Quantitative analysis and simultaneous equation method for estimation of Domperidone and Naproxen by UV-Visible Spectrophotometry in bulk Tablet Dosage Form. Research Article .2020 3-5.
48.    Kumas S,et al .Development and Validation of Simultaneous Equation Estimation Method for kanamycin and Ketoconazole by UV-Visible Spectrophotometric Method.International Journal of Pharmaceutical Science and Science. 2014 , 60-70.
49.    Vyas A.J, et al.Simultaneous Estimation of Lornoxicam and Parcetomol by Vierordt’s Method in API and in Synethic Mixture.International Journal of ChemTech Research. 2011, 1269-1273.
50.    Kumari B ,et al. Spectrophotometric Method for Simultaneous Estimation of Olmesartan Medoximil and Hydrochlorthiazide in tablets. Research Journal of Pharmaceutical ,Biological and Chemical Science . 2013, 104-110.
51.    Vyas AJ,et al. Vierodt’s and Q-Absorption Ratio Spectrophotometric methods for simultaneous determination of Drotaverine HCL and PCM in tablet dosage form.Asian Journal of Research in chemistry. 1258-1261.
52.    Oza CK,et al.Dual wavelength spectrophotometric method for the simultaneous determination of paracetamol and nambuteone in API and in tablet dosage form. Asian journal of Pharmacetuical Analysis. 2012, 122-127.
53.    Sawant L,et al.Spectrophotometric method for simultaneous estimation of rabeprazole sodium and accelofenac from combined capsule dosage form. 2011,193-197
54.    Khedekar P, et al. Application of vierodt,s and absorption correction spectrophotometric methods for estimation of rosiglitazone maleate and glimperide in tablets.Digest Journal of nanomaterials and Biostructures.2009,739-746.
55.    Rohitas M, et al . Development of simultaneous spectrophotometric method of mesalamine and prednisolone in same dosage form.International Journal of Application Pharmacetuical. 2010,1-11
56.    Game MD, et al. Absorbance correction and vierodt’s method for simultaneous determination of ofloxacin and nitazoxanide in combined dosage form. Research journal of pharmacy and Technology. 2010,113-117.
57.    D.sonawane and Narwate B.M.Application of UV spectrophotometric method development and validation for estimation of Tezalafor and Ivacaftor in Pharmacetuical dosage form.World Journal of Pharmacetuical Research. 213-218,2018.
58.    Chandana V, et al . Estimation of ondaserton and esomeprazole in dosage forms by vierodts method. Journal of Global Trends in Pharmacetuical Science.2014,1849-1853.
59.    Abdul R, et al.Development and validation of UV spectrophotometric method for simultaneous estimation of ciprofloxacin and Tinidazole in tablet dosage form.International Journal of Pharmacy and Industrial Research. 2013,295-300.
60.    Shinde G, and Aloorkar N.Development and validation of UV spectrophotometric method for simultaneous estimation of propranolol HCL and rosuvastatin calcium inbulk drug and pharmaceutical dosage form.International journal of advance in pharmaceutics.2015,2320-4923.
61.    Rooseweet C, et al.Simultaneous estimation of drotaverine HCL and mefenamic acid in tablet dosage form.Asian journal of Chemistry.2010,843-849.
62.    Sharma S and Manocha N.Estimation of sitagliptin phosphate and simvastatin and validation of proposed method in a combined marketed tablet dosage form by simultaneous equation method.Pharmacetuical Research. 2012,144-147.
63.    Dhandar A, et al.Method for simultaneous estimation of Quinafamide and Mebendazole in house pharmaceutical formulation. Journal of pharmaceutical technology,2018,2321-2217.
64.    Girdhrai J, et al.Simultaneous estimation of Atenolol and Amlodipine besylate in tablet formulation by vierodt’s method using UV-Spectrophotometry,International Research of Pharmacy.2012,248-260.
65.    Dsouza P and Koland M.Simultaneous estimation of Famotidine and Rabeprazole sodium method development and validation by UV-Spectrophotometric method.International Journal of Pharmacy and pharmaceutical science. 2015,257-260.
66.    Merukar S, et al.Simultaneous spectrophotometric methods for estimation of levocitrizine and pseudoephedrine in Pharmacetuical tablet dosage form.Journal of pharmaceutical science and research,2009,38-42.
67.    Jain A, et al.Development of simultaneous spectrophotometric method of Amoxicillin trihydrate and rantidine bismuth citrate in same dosage form. International journal of chemistry research. 2010,41-45.
68.    Nagulwar V, et al.Development of simultaneous spectrophotometric method of Valdecoxib and Tizanidine by Vierodt’s and Q-Analysis UV spectrophotometry.Indian journal of pharmaceutical science.2014,624-630.
69.    Patel P,et al. Simultaneous determination of prednisolone and aspirin by vierordts method.IJPSR. 2020,2620-2627.
70.    Begum H,Rizwan S et al. Development and validation of stability indicating UV spectrophotometric simultaneous equation method for determination of ezetimibe and glimepride in bulk and market formulation.IJRDPL. 2015,1412-1421
71.    Delvadiya K, et al. Spectrophotometric Simultaneous Analysis of Paracetamol, Propyphenazone and Caffeine in Tablet Dosage Forms.International Journal of Pharmacetuical Science and Research. 2011 ,171-175.
72.    Vichare V,Mujgond P .Simultaneous spectrophotometric determination of paracetamol and caffeine in tablet formulation.,IJPRIF. 2010; 2(4): 2512‐16.
73.    Atole DM and Rajput HH. Ultraviolet Spectroscopy and Its Pharmaceutical Applications- A brief Review. Asian Journal of Pharmaceutical and Clinical Research .2018, 59-66.
74.    Venkasetan S and Kannappan N .Simultaneous Spectrophotometric Method for Determination of Emtricitabine and Tenofovir Disoproxil Fumarate in Three-Component Tablet Formulation Containing Rilpivirine Hydrochloride. International Scholarly Research Notice. 2014, 1-7.
75.    Pranitha D, et al. Simultaneous estimation of Emtricitabine, Tenofovir disoproxil fumarate, and Rilpivirine in bulk form by RP-HPLC method. Journal of Pharmacy Research. 2012, 4600–4602.
76.    Anandakumar K,et al.Development and validation of Emtricitabine and Tenofovir disoproxil fumarate in pure and in fixed dose combination by UV spectrophotometry. Digest Journal of Nanomaterials and Biostructure. 2011, 1085–1090.
77.    Sacide A and Suna T. Determination Of Tartrazine and Ponceau-4R in Various Food Samples by Vierordt’s Method and Ratio Spectra First – Order Derivative UV Spectrophotometry. ELSEVIER Journal of Food Composition and Analysis. 2002 ,667-683.
78.    Sacide A and Suna T. Simultaneous determination of Indigotin and Ponceau – 4R in food Samples by using Vierordt’s Method, ratio spectra first order derivative and Derivative UV spectrophotometry.ELSIEVER Journal of Food Composition and Analysis. 2003, 517-530.
79.    Sen K, Hinsu D, et al.Analytical method development and validation for simultaneous estimation of Tenegliptin hydrobromide hydrate and metformin hydrochloride from its pharmaceutical dosage form by three different UV spectrophotometric methods. Journal of Applied science and pharmaceutical science. 2016,57-65.
80.    Patil P, Diet alesh D and Baris S. Simultaneous estimation of etodolac and thiocolchicoside in bulk and in tablets formulation by UV-Spectrophotometry. Chemical Industry and Chemical Engineering Quartery. 2014, 9-17
81.    Agarwal A, et al.Development of simultaneous Spectrophotometric method of Mesalamine and prednisolone in same dosage form. International Journal of Applied Science and Pharmacetuical Science. 2010, 8-11
82.    Chitlange S, et al. Simultaneous estimation of Diacerin and Accelofenac in tablet dosage form. Scholar Research Library. 2010,335-341.
83.    Manwar J, et al. Application of simultaneous equation method for determination of azithromycin and cefixime trihydrate in tablet formulation. Research Journal of Pharmacy and Technology. 2017,108-112.
84.    Affas S, et l. Spectrophotometric method for simultaneous estimation of Dapoxetine and some Phosphodiestrase 5 inhibitors in new combination. Research Journal of Pharmacy and Technology. 2019, 5193-5198
85.    Daharwal S,et al. Application of simultaneous equation method for determination of Atenolol and Losartan in tablet formulation. Research Journal of Pharmacy and Technology. 2016, 415-420.
86.    Bhadane R,et al. Simultaneous estimation of Olmesartan Medoxomil and Hydrochlorthiazide by spectrophotometry in Tablet formulation. Research Journal of Pharmacy and Technology.2010,1047-1049.
87.    Nanda RK,et al. Simultaneous Spectrophotometric Methods for estimation of Cefixime and Erdosteine in synthetic mixture. Research Journal of Pharmacy and Technology. 2009,582-584.
88.    Srivastava B, et al. Simultaneous Spectrophotometric estimation and validation of Metformin Hydrochloride and Glibendamide in bulk drug and pharmaceutical dosage form. Research Journal of Pharmacy and Technology. 2010, 109-112.
89.    Devadase C, et al. A spectrophotometric assay for simultaneous analysis of Mifepristone and Misoprostol in Tablets using Vierodt’s and Absorbance ration method. Research Journal of Pharmacy and Technology. 2012,46-48.
90.    Game MD, et al. Absorbance correction and vierodt’s Spectrophotometric method for simultaneous determination of Ofloxacin and Nitazoxanide in combined dosage form. Research Journal of Pharmacy and Technology.2010.214-216.
91.    RavalH.V, et al. Estimation of Metoprolol Tartrate and chlorthalidone in combined dosage form by UV- Spectrophotometric method. Research Journal of Pharmacy and Technology. 2011,1132-1134.

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