Dibyajyoti Saha, Mayukh Jana, Supradip Mandal
Dibyajyoti Saha*1, Mayukh Jana2 Supradip Mandal2
1School of Pharmacy, Chouksey Engineering College, Lal Khadan, Masturi Road, Bilaspur-495004,C.G.
2Bharat Technology, Banitabla, Uluberia, Howrah-711316
Volume - 1,
Issue - 2,
Year - 2011
The molecular pharmacology involving aspects of biological, medical and pharmaceutical sciences. It is concerned with invention, discovery, design, identification and preparation of biologically active compounds, the study of their metabolism, the interpretation of their mode of action at the molecular level. The physiology based drug discovery follows physiological readouts and by contrast, the road of target based drugs discovery begins with identifying the function of a possible therapeutic target and its role in disease. The validation of a molecular target in vitro usually proceeds the validation of a therapeutic concept in vivo; together this defines its clinical potential. The present article gives disease mechanisms of target discovery and outline of target validation with its pathways.
Cite this article:
Dibyajyoti Saha, Mayukh Jana, Supradip Mandal. Target Discovery and Validation: Advances in Molecular Pharmacology. Asian J. Pharm. Ana. 1(2): April-June 2011; Page 27-28.