Author(s):
Devshree Yashwantbhai Patel, Javesh Kashinath Patil
Email(s):
devshreeppatell3@gmail.com
DOI:
10.52711/2231-5675.2024.00032 
Address:
Devshree Yashwantbhai Patel, Javesh Kashinath Patil
Department of Pharmaceutical Quality Assurance,
P.S.G.V.P. Mandal’s College of Pharmacy, Shahada, Dist – Nandurbar, 425409.
Associate Professor, Department of Pharmaceutical Quality Assurance,
P.S.G.V.P. Mandal’s College of Pharmacy, Shahada, Dist – Nandurbar, 425409.
*Corresponding Author
Published In:
Volume - 14,
Issue - 3,
Year - 2024
ABSTRACT:
The field of analytical chemistry comprises many methodologies that are essential in ascertaining the chemical makeup of various substances. This review centers on two widely used techniques: high-performance liquid chromatography (HPLC) and UV-visible spectroscopy. By measuring absorbance using the Beer-Lambert rule, UV-visible spectroscopy can reveal the concentration of absorbing species. It is based on how light and matter interact, with absorption taking place as a result of molecular electronic transitions. HPLC, on the other hand, uses high pressure to separate mixture components according to how well they bind to a stationary phase. Its versatility is attributed to a number of different separation methods, including adsorption, partition, ion exchange, and size exclusion chromatography. In order to guarantee the dependability of analytical techniques, method development and validation are essential. It is necessary to evaluate validation factors, including specificity, accuracy, precision, linearity, and robustness, to ensure that a method is appropriate for the purpose for which it is intended. An analysis of the literature reveals various HPLC techniques for the analysis of ramipril, an ACE inhibitor used to treat heart failure and hypertension. These investigations have examined a range of mobile phases and columns, demonstrating the flexibility of HPLC in pharmaceutical analysis. By blocking the renin-angiotensin-aldosterone system (RAAS), ramipril works by decreasing inflammation and vasoconstriction. An extensive review of analytical chemistry techniques is given in this abstract, with special emphasis on the methods' significance for pharmaceutical analysis and drug development.
Cite this article:
Devshree Yashwantbhai Patel, Javesh Kashinath Patil. A Systematic Review of Method Development and Validation for Ramipril Analysis using HPLC in Cardiovascular Research. Asian Journal of Pharmaceutical Analysis. 2024; 14(3):180-4. doi: 10.52711/2231-5675.2024.00032
Cite(Electronic):
Devshree Yashwantbhai Patel, Javesh Kashinath Patil. A Systematic Review of Method Development and Validation for Ramipril Analysis using HPLC in Cardiovascular Research. Asian Journal of Pharmaceutical Analysis. 2024; 14(3):180-4. doi: 10.52711/2231-5675.2024.00032 Available on: https://ajpaonline.com/AbstractView.aspx?PID=2024-14-3-13
REFERENCES:
1. Skoog D. A, Nieman TA, Holler FJ. Principles of instrumental analysis. 5th ed. London: Stanford University, Saunders College Publications. 1998; 1-4.
2. Jeffery G.H, Bassett J, Mendham J, And Denney R C., Vogel’s Textbook of Quantitative Chemical Analysis, 5th Ed., Addison Wesley Longman Inc, Singapore. 2001: 4-5.
3. Erwing G.W., Instrumental Methods of Chemical Analysis, 2nd Ed., Mcgraw Hill Publishing Company Inc. 1960: 1-3.
4. Skoog D.A., Holler F.J. And Nieman T.A., Principles of Instrumental Analysis, 5th Ed., Thomson Brooks/Cole Asia Pvt. Ltd, Singapore. 2004: 4-7.
5. Verma G. and Dr. Mishra M.; Development and Optimization of UV-Vis Spectroscopy-A Review. World Journal of Pharmaceutical Research. 2018; 7(11) : 1170-1180
6. A Review on Uv Visible Spectroscopy. International Journal of Pharmaceutical Research and Applications. 2022; 7(5): 1144-1151 DOI: 10.35629/7781-070511441151
7. Thammana; review of high-performance liquid chromatography (hplc). RRJPA. 2016; 5(2):22-28
8. Gita Chawla, Krishna Kr. Chaudhary. A review of HPLC technique covering its pharmaceutical, environmental, forensic, clinical and other application. 2019; 6(2): 27-39
9. Jacqueline M.R. Belanger J.R. Jocelyn Pare and Michel Sigouin, High Performance Liquid Chromatography (HPLC): Principle and Application. 1997:38-58
10. Rao, Tentu. Validation of Analytical Methods. Calibration and Validation of Analytical Methods – A Sampling of Current Approaches, edited by Mark Stauffer, IntechOpen, 2018. 10.5772/intechopen.72087.
11. Thapar, S., Chawla, A., and Gupta, G. K. A concise review on method development and validation parameters. GSC Biological and Pharmaceutical Sciences. 2022; 19(1): 66–77. https://doi.org/10.30574/gscbps.2022.19.1.0136
12. Patel Kiran, and Patil Javesh. Development and Validation of UV-Spectroscopy and UHPLC Method for Gemfibrozil in Bulk Drug and Pharmaceutical Dosage Form [Data set]. In International Journal of Pharma Research and Technology. 2023; 2(3). Zenodo. https://doi.org/10.5281/zenodo.10039607
13. Chavan, S. D., and Desai, D. M. Analytical method validation: A brief review. World Journal of Advanced Research and Reviews. 2022; 16(2): 389–402. https://doi.org/10.30574/wjarr.2022.16.2.1165
14. Patil M A, and Patil J K. Stability Indicating Method Development and Validation of Ziprasidone by using RP-HPLC Method. 2023. https://doi.org/10.5281/zenodo.8394540
15. Lavanya Chowdary G, Ravisankar P. Int. J. Pharm. Sci. Rev. Res., 2020; 61(2): 1-7
16. Eserian, J. K., and Lombardo, M. Method validation in pharmaceutical analysis: from theory to practical optimization. Innovations in Pharmacy. 2015; 6(1). https://doi.org/10.24926/iip.v6i1.376
17. Kapil, Patil and Sunil, Pawar and Patil, Javesh. Development and Validation of RP-HPLC Method for Simultaneous Estimation Of Amoxicillin And Dicloxacillin in Bulk Drug and Capsules. 2014.
18. Determination of Ramipril in Pharmaceutical Preparations By High-Performance Liquid Chromatography. International Journal of Pharmaceutical Sciences Review and Research. 2010; 1(1): 39–42.
19. Rajoriya, V., Soni, A., and Kashaw, V. Method Development and Validation of Fast Dissolving Tablet of Ramipril by HPLC Method. International Journal of Pharmacy and Pharmaceutical Sciences. 2016; 8(3): 174–178. https://innovareacademics.in/journals/index.php/ijpps/article/view/9619
20. Abdallah, N. A., El-Brashy, A., Ibrahim, F., and El-Awady, M. I. Micellar eco-friendly HPLC method for simultaneous analysis of ternary combination of aspirin, atorvastatin and ramipril: application to content uniformity testing. BMC Chemistry. 2023; 17(1). https://doi.org/10.1186/s13065-023-00929-y
21. Rajput. Simultaneous Estimation of Ramipril and Amlodipine in Bulk and tablet Dosage form by RP-HPLC Method. Journal of Applied Pharmaceutical Science. 2012; https://doi.org/10.7324/japs.2012.2724
22. Yada, D., Yada, D., Rajeshwari, T., Madhavilatha, M., and Rani, G. T. A New Validated Rp-HPLC Method for The Simultaneous Estimation Of Ramipril And Olmesartan Medoxomil. International Journal of Pharmacy. 2016; 6(1): 177–185. https://www.pharmascholars.com/articles/a-new-validated-rphplc-method-for-the-simultaneous-estimation-of-ramipril-and-olmesartan-medoxomil.pdf
23. M. Prasada Rao, M. Srikanth, K. Umamaheswari. Simultaneous estimation of Ramipril and Olmesartan Medoximil by RP-HPLC Method.International Journal of Pharmaceutical Chemistry and Analysis. 2017; 4(4): 106-111. DOI: 10.18231/2394-2797.2017.0024
24. Sharma, R., Khanna, S., and Mishra, G. P. Development and validation of RP-HPLC method for simultaneous estimation of ramipril, aspirin and atorvastatin in pharmaceutical preparations. E-journal of Chemistry. 2012; 9(4): 2177–2184. https://doi.org/10.1155/2012/89169510.
25. Hitendra Choudhary, Bhagwan Yadav, Pankaj Patel, Prabhat Das, Sujit Pillai. Formulation and Evaluation of Ramipril Fast Dissolving Tablet using Solid Dispersion. Research J. Pharm. And Tech. 2019; 12(8): 3764-3772. Doi: 10.5958/0974-360X.2019.00645.0
26. Indian Pharmacopoeia, 2007 (Vol. 3). Page No 1648-1469