Author(s): Vaishali C. Kulkarni, Manisha D. Khemnar, Amruta C. Menkudale, Dr. Rupesh J. Patil, Dr. Kishor V. Otari

Email(s): vaishalikulkarni115@gmail.com

DOI: 10.5958/2231-5675.2020.00009.5   

Address: Vaishali C. Kulkarni*1, Manisha D. Khemnar1, Amruta C. Menkudale1, Dr. Rupesh J. Patil2, Dr. Kishor V. Otari1
1Navsahyadri Insititute of Pharmacy, Naigaon, Nasrapur, Pune, 412213.
2Navsahyadri Group of Institutes – Faculty of Engineering, Naigaon, Nasrapur, Pune, .412213.
*Corresponding Author

Published In:   Volume - 10,      Issue - 1,     Year - 2020


ABSTRACT:
Around a century ago, in 1916, the term ‘hydrotropy’ was coined by the scientist Carl A. Neuberg to concentrate on anionic organic salts which significantly enhanced the aqueous solubility of weakly soluble solutes1. The thin layer chromatography (TLC) of drugs are usually performed with the help of solvents like butyl amine, toluene, ether, chloroform, light petroleum, ethyl acetate, ethanol, hexane, xylene and phenol. The majority of which are much expensive and toxic1-3. Now a days, aqueous solubility of drugs is major problem in pharmaceutical field. Hydrotropic agents are employed as mobile phase for estimation of poorly aqueous soluble drugs by TLC technique. The current review takes the readers throughout a brief summary, geometrical Features of hydrotropic agents, and their different advances toward Chromatographic techniques. Moreover, this review would provide an insight of the future perspectives concerned with the TLC and hydrotropism. In future, hydrotropic solutions shall prove a boon in TLC and high performance thin layer chromatography (HPTLC) analysis of a vast number of drugs thereby limiting the use of organic solvents to a great extent.


Cite this article:
Vaishali C. Kulkarni, Manisha D. Khemnar, Amruta C. Menkudale, Dr. Rupesh J. Patil, Dr. Kishor V. Otari. Hydrotropy: A Boon in Thin layer Chromatography A Review. Asian J. Pharm. Ana. 2020; 10(1):40-43. doi: 10.5958/2231-5675.2020.00009.5


Recomonded Articles:

Author(s): Kirthi A, Shanmugam R, Mohana Lakshmi S , Ashok Kumar CK, Padmini K, Shanti Prathyusha M, Shilpa V

DOI:         Access: Open Access Read More

Author(s): Hamid Khan, Javed Ali

DOI: 10.5958/2231-5675.2017.00020.5         Access: Open Access Read More

Author(s): G. Krishnamoorthy, C. Diana Priyadarshini, R. Senthamarai

DOI:         Access: Open Access Read More

Author(s): Paras Virani, Rajanit Sojitra, Hasumati Raj, Vineet Jain

DOI: 10.5958/2231-5675.2015.00025.3         Access: Open Access Read More

Author(s): P. Janaki Pathi, N. Appala Raju, G.Parvathalu

DOI:         Access: Open Access Read More

Author(s): Saroj Kumar Raul, Bukkuru Spandana, Patibandla Sameera, Vegiraju Vikitha

DOI:         Access: Open Access Read More

Author(s): Mansi J. Chaudhari, Suraj R. Chaudhari, Shailesh S. Chalikwar, Atul A. Shirkhedkar

DOI: 10.5958/2231-5675.2018.00008.X         Access: Open Access Read More

Author(s): S. Vidyadhara, RLC Sasidhar, B. Venkateswara Rao, P. Ratna Kumari

DOI:         Access: Open Access Read More

Author(s): Khushboo Patel*, Dhara Patel, Jaya Dwivedi, Priyanka Newal, Dhananjay Meshram

DOI: 10.5958/2231-5675.2017.00039.4         Access: Open Access Read More

Author(s): B. Thangabalan, M. Salomi, N. Sunitha, S. Manohar Babu

DOI:         Access: Open Access Read More

Author(s): Samer Housheh, Saleh Trefi, M. Fawaz Chehna

DOI: 10.5958/2231-5675.2017.00010.2         Access: Open Access Read More

Author(s): Sri Lakshmi D, Jane T Jacob, Srinivasa Sastry D, Satyanarayana D

DOI: 10.5958/2231-5675.2017.00005.9         Access: Open Access Read More

Author(s): Hamid Khan, Mushir Ali, Alka Ahuja, Javed Ali

DOI:         Access: Open Access Read More

Author(s): Madhavi R., Mohana Krishna A., Shobha Rani G., Mounika D.

DOI: 10.5958/2231-5675.2015.00008.3         Access: Open Access Read More

Asian Journal of Pharmaceutical Analysis (AJPA) is an international, peer-reviewed journal, devoted to pharmaceutical analysis...... Read more >>>

RNI: Not Available                     
DOI: 10.5958/2231–5675 

Popular Articles


Recent Articles




Tags