Author(s): Akshay Waghmare, Ganesh Taware, Shrikrishna Baokar, Santosh Undare

Email(s): Email ID Not Available

DOI: 10.5958/2231-5675.2019.00003.6   

Address: Akshay Waghmare1, Ganesh Taware2, Shrikrishna Baokar1*, Santosh Undare3
1Department of Pharmaceutical Chemistry, SVPM’S College of Pharmacy, Malegaon (Bk), Tal- Baramati, Dist- Pune, Maharashtra 413115.
2Department of Pharmaceutics, SVPM’S College of Pharmacy, Malegaon (Bk), Tal- Baramati, Dist- Pune, Maharashtra 413115.
3PG Department of Chemistry, Balbhim Arts, Science and Commerce College, Beed, Maharashtra 431122.
*Corresponding Author

Published In:   Volume - 9,      Issue - 1,     Year - 2019


ABSTRACT:
Simple sensitive and accurate spectrophotometric methods were developed for determination of poorly water soluble Amlodipine Besylate in pure and pharmaceutical dosage form using hydrotropic agents ammonium acetate. Hydrotropy is a good choice for replacing organic solvents used for this kind of drugs to reduce the cost and hazards of the analytical method. Amlodipine Besylate shows maximum absorption at 362 nm in 0.5 M of the hydrotropic agents. Beer’s law was found to be obeyed in the concentration range of 5 - 25 µg/mL for the hydrotrope. Limit of detection was found to be 1.102µg/mL and limit of quantification was 3.278 µg/mL for ammonium acetate. The results were in a good agreement with those obtained with official USP method.


Cite this article:
Akshay Waghmare, Ganesh Taware, Shrikrishna Baokar, Santosh Undare. Ecofriendly Validated Spectrophotometric Method for the Estimation of Amlodipine Besylate by using Hydrotropic Solubilization Method. Asian J. Pharm. Ana. 2019; 9(1):08-10. doi: 10.5958/2231-5675.2019.00003.6


Recomonded Articles:

Author(s): K. Pramod, Shahid H. Ansari, Javed Ali

DOI:         Access: Open Access Read More

Author(s): Santosh Gada, Anand Kumar Y, Saritha, C. Mallikarjuna Setty

DOI: 10.5958/2231-5675.2018.00036.4         Access: Open Access Read More

Author(s): Kirthi A, Shanmugam R, Mohana Lakshmi S , Ashok Kumar CK, Padmini K, Shanti Prathyusha M, Shilpa V

DOI:         Access: Open Access Read More

Author(s): Sushil D. Patil, Sayali K. Chaure, Maswood Ahmed Hafizur Rahman, Prajkta U. Varpe, Sanjay Kshirsagar.

DOI: 10.5958/2231-5675.2017.00004.7         Access: Open Access Read More

Author(s): Hamid Khan, Javed Ali

DOI: 10.5958/2231-5675.2017.00020.5         Access: Open Access Read More

Author(s): G. Krishnamoorthy, C. Diana Priyadarshini, R. Senthamarai

DOI:         Access: Open Access Read More

Author(s): P. Janaki Pathi, N. Appala Raju, G.Parvathalu

DOI:         Access: Open Access Read More

Author(s): Paras Virani, Rajanit Sojitra, Hasumati Raj, Vineet Jain

DOI: 10.5958/2231-5675.2015.00025.3         Access: Open Access Read More

Author(s): Khushboo Patel*, Dhara Patel, Jaya Dwivedi, Priyanka Newal, Dhananjay Meshram

DOI: 10.5958/2231-5675.2017.00039.4         Access: Open Access Read More

Author(s): B. Thangabalan, M. Salomi, N. Sunitha, S. Manohar Babu

DOI:         Access: Open Access Read More

Author(s): Mansi J. Chaudhari, Suraj R. Chaudhari, Shailesh S. Chalikwar, Atul A. Shirkhedkar

DOI: 10.5958/2231-5675.2018.00008.X         Access: Open Access Read More

Author(s): Saroj Kumar Raul, Bukkuru Spandana, Patibandla Sameera, Vegiraju Vikitha

DOI:         Access: Open Access Read More

Author(s): S. Vidyadhara, RLC Sasidhar, B. Venkateswara Rao, P. Ratna Kumari

DOI:         Access: Open Access Read More

Author(s): Yogita R. Indalkar, Aloorkar N.H.

DOI: 10.5958/2231-5675.2015.00028.9         Access: Open Access Read More

Asian Journal of Pharmaceutical Analysis (AJPA) is an international, peer-reviewed journal, devoted to pharmaceutical analysis...... Read more >>>

RNI: Not Available                     
DOI: 10.5958/2231–5675 

Popular Articles


Recent Articles




Tags