Author(s): M. Pranati, N. Usha Rani, B. Pravallika

Email(s): pranatimandalemula@gmail.com

DOI: 10.52711/2231-5675.2023.00017   

Address: M. Pranati, N. Usha Rani, B. Pravallika
Maharajah’s College of Pharmacy Affiliated to Andhra University, Phool Baugh, Vizianagaram, 535002.
*Corresponding Author

Published In:   Volume - 13,      Issue - 2,     Year - 2023


ABSTRACT:
A Simple and reliable Zero cross technique for simultaneous estimation of Rosuvastatin Calcium and Fenofibrate in tablets by using UV derivative method was developed. The quantitative determination of the drugs was carried out using the Zero cross values measured at 235nm and 273nm for Rosuvastatin Calcium and Fenofibrate respectively. The Calibration curves constructed at these wavelengths for the determination of the linearity in the concentration range of 5-25µg/mlfor both the selected drugs. The low relative standard deviation values indicate good precision and higher recovery values indicate accuracy of the proposed method. The developed zero cross technique was found to be simple, accurate, precise, specific, sensitive and reproducible which can be directly and easily applied tomarketed formulations.


Cite this article:
M. Pranati, N. Usha Rani, B. Pravallika. A New Zero Cross Technique for Simultaneous Estimation of Rosuvastatin Calcium and Fenofibrate in Tablets by UV Derivative Spectroscopic Method. Asian Journal of Pharmaceutical Analysis. 2023; 13(2):99-2. doi: 10.52711/2231-5675.2023.00017

Cite(Electronic):
M. Pranati, N. Usha Rani, B. Pravallika. A New Zero Cross Technique for Simultaneous Estimation of Rosuvastatin Calcium and Fenofibrate in Tablets by UV Derivative Spectroscopic Method. Asian Journal of Pharmaceutical Analysis. 2023; 13(2):99-2. doi: 10.52711/2231-5675.2023.00017   Available on: https://ajpaonline.com/AbstractView.aspx?PID=2023-13-2-6


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DOI: 10.5958/2231–5675 


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