Author(s): S. P. Chougule

Email(s): Email ID Not Available

DOI: 10.52711/2231-5675.2024.00011   

Address: S. P. Chougule*
Lecturer, Shree Ambabai Talim Sanstha’s Diploma in Pharmacy College, Miraj.
*Corresponding Author

Published In:   Volume - 14,      Issue - 2,     Year - 2024


ABSTRACT:
In present study, on a Jasco V-730 spectrophotometer, the method for estimating acetazolamide was used, with ethanol: distilled water (5:5) serving as the solvent. For acetazolamide, the recovery analysis research indicates recoveries of 102.55%, 102.68%, and 103.35% for various concentrations of the spiked medication. For quantifying acetazolamide in bulk and tablet dosage form, an RP-HPLC method was created and validated with mobile phase acetonitrile: water (80:20). For acetazolamide, the assay (% w/w) was found 98.6 %, 98.5 %, 98.9 %. The flow rate was 1ml/min. The sample volume was 20.00µl. Run time 5 min and retention time was 2.044.


Cite this article:
S. P. Chougule. Development of Analytical method by UV and HPLC of Acetazolamide in bulk and tablet dosage form. Asian Journal of Pharmaceutical Analysis. 2024; 14(2):60-4. doi: 10.52711/2231-5675.2024.00011

Cite(Electronic):
S. P. Chougule. Development of Analytical method by UV and HPLC of Acetazolamide in bulk and tablet dosage form. Asian Journal of Pharmaceutical Analysis. 2024; 14(2):60-4. doi: 10.52711/2231-5675.2024.00011   Available on: https://ajpaonline.com/AbstractView.aspx?PID=2024-14-2-2


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