Author(s): Pankaj, Pramod Kumar, Aman Kapoor, Priyanka, Puneet Kumar, Saweta Kumari


DOI: 10.52711/2231-5675.2023.00006   

Address: Pankaj, Pramod Kumar, Aman Kapoor, Priyanka, Puneet Kumar, Saweta Kumari
Dreamz College of Pharmacy, Khilra (Sundernagar) 175036.
*Corresponding Author

Published In:   Volume - 13,      Issue - 1,     Year - 2023

LC-TOF-MS is powerful analytical technique. It is a combination of two techniques one of which is belongs to chromatography and other is from spectroscopy. Chromatography is separation technique and perform both techniques separately it is very time consuming but combined both techniques to save time and provide better results. This represents the potential of liquid chromatography with (quadrupole) time-of-flight mass spectrometry [LC-(Q)TOF-MS] in examining the presence of pesticide metabolites in food and water samples. This method portrays a quick enhanced screen for blood and urine specimens in post-mortem, driving under the influence and drug facilitated sexual assault forensic toxicology casework. (LC–MS) is an analytical technique that amalgamate the physical separation capability of liquid chromatography with the mass analysis capability of mass-spectrometry (MS).This technique can be used in analysis of pharmacokinetics, proteomics/metabolomics, development drug, analysis of pesticides in vegetables, analysis of medicinal panaxherbs for metabolomic research, identification of diphenhydramine in segment sample, investigation of pesticides metabolites in food and water etc.

Cite this article:
Pankaj, Pramod Kumar, Aman Kapoor, Priyanka, Puneet Kumar, Saweta Kumari. LC–Tof-Ms an Influential Hyphenated Technique and its Application. Asian Journal of Pharmaceutical Analysis. 2023; 13(1):35-1. doi: 10.52711/2231-5675.2023.00006

Pankaj, Pramod Kumar, Aman Kapoor, Priyanka, Puneet Kumar, Saweta Kumari. LC–Tof-Ms an Influential Hyphenated Technique and its Application. Asian Journal of Pharmaceutical Analysis. 2023; 13(1):35-1. doi: 10.52711/2231-5675.2023.00006   Available on:

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