Author(s): Swanand Patharkar, Kalpak Gajbhiye, Nawaz Hakam, Aman Vyawahare

Email(s): swanandrpatharkar07@gmail.com , gajbhiyekalpak@gmail.com

DOI: 10.52711/2231-5675.2022.00018   

Address: Swanand Patharkar, Kalpak Gajbhiye, Nawaz Hakam, Aman Vyawahare
Department of Quality Assurance, P.R. Pote Patil College of Pharmacy, Amravati-444604.
*Corresponding Author

Published In:   Volume - 12,      Issue - 2,     Year - 2022


ABSTRACT:
A rapid, sensitive and accurate method for Estimation of Anti- Histamine in Tablet Dosage Form by RP-HPLC. Mobile phase was Methanol: 0.1% Ortho phosphoric acid (80:20% v/v). Flow rate was 0.9 ml/min. The detection Wavelength was 227 nm. The injection volume was 20-µl. The proposed method was validated for selectivity, precision, linearity, and accuracy. All validation parameters were within the acceptable range. Linearity studies for Levamisole was performed (10-60µg/ml). The %RSD for accuracy found to be less than2%. Assay was found to be 99.17 to 101.65 respectively The range of 10-60µg /ml was selected for the linearity of a standard Levamisole. The 80%, 100% and 120% levels of recovery study were selected to perform the recovery study. Linearity studies for Levamisole was performed on (10-60µg /ml).


Cite this article:
Swanand Patharkar, Kalpak Gajbhiye, Nawaz Hakam, Aman Vyawahare. Development and Validation of New Analytical Method for Estimation of Anthelmintic in Tablet Dosage Form. Asian Journal of Pharmaceutical Analysis. 2022; 12(2):99-4. doi: 10.52711/2231-5675.2022.00018

Cite(Electronic):
Swanand Patharkar, Kalpak Gajbhiye, Nawaz Hakam, Aman Vyawahare. Development and Validation of New Analytical Method for Estimation of Anthelmintic in Tablet Dosage Form. Asian Journal of Pharmaceutical Analysis. 2022; 12(2):99-4. doi: 10.52711/2231-5675.2022.00018   Available on: https://ajpaonline.com/AbstractView.aspx?PID=2022-12-2-6


REFERENCES:
1.    Malviya VR, Pande SD, Bobade NN. Preparation and Evaluation of Sustained Release Beads of Zolmitriptan Hydrochloride. Research Journal of Pharmacy and Technology. 2019;12(12):5972-6.
2.    Malviya V, Thakur Y, Gudadhe SS, Tawar M. Formulation and evaluation of natural gum based fast dissolving tablet of Meclizine hydrochloride by using 3 factorial design 2. Asian Journal of Pharmacy and Pharmacology. 2020;6(2):94-100.
3.    Malviya VR, Pande SD. Road CKN. Preparation ad Evaluation of Zolmitriptan Hydrochloride Lozenge. J Pharma Res. 2019;8(8):624-9.
4.    Malviya V, Manekar S. Design, Development and Evaluation of Aceclofenac and Curcumin Agglomerates by Crystallo Co-Agglomeration Technique. Research Journal of Pharmacy and Technology. 2021 Mar 18;14(3):1535-41.
5.    Malviya V, Ladhake V, Gajbiye K, Satao J, Tawar M. Design and Characterization of Phase Transition System of Zolmitriptan Hydrochloride for Nasal Drug Delivery System. International Journal of Pharmaceutical Sciences and Nanotechnology. 2020 May 31;13(3):4942-51.
6.    Malviya VR, Tawar MG. Preparation and Evaluation of Oral Dispersible Strips of Teneligliptin Hydrobromide for Treatment of Diabetes Mellitus. International Journal of Pharmaceutical Sciences and Nanotechnology. 2020 Jan 31;13(1):4745-52.
7.    Malviya V, Pande S. Development and Evaluation of Fast dissolving Film of Fluoxetine hydrochloride. Research Journal of Pharmacy and Technology. 2021 Oct 31;14(10):5345-50.
8.    Malviya V. Preparation and Evaluation of Emulsomes as a Drug Delivery System for Bifonazole. Indian Journal of Pharmaceutical Education and Research. 2021 Jan 1;55(1):86-94.
9.    Malviya V, Burange P, Thakur Y, Tawar M. Enhancement of Solubility and Dissolution Rate of Atazanavir Sulfate by Nanocrystallization. Indian Journal of Pharmaceutical Education and Research. 2021 Jul 1;55(3):S672-80.
10.    Malviya V. Design and Characterization of Thermosensitive Mucoadhesive Nasal Gel for Meclizine Hydrochloride. International Journal of Pharmaceutical Sciences and Nanotechnology. 2022 Feb 28;15(1):5782-93.
11.    Selvaraj U, Manna PK, Kamarajan K. Screening of Complement Stimulating Activity of Lindernia madayiparense Extracts. Research Journal of Pharmacy and Technology. 2019;12(9):4324-6.
12.    Akhtar J, Pasha TY, Padaria M, Shah B, Mansuri N, Prajapati K. Spectrophotometric Methods for Simultaneous Estimation of Tramadol Hydrochloride and Diclofenac Sodium in Combined Dosage Form. Research Journal of Pharmacy and Technology. 2013;6(3):227-31.
13.    Sujana K, Sankar DG, Abbulu K. Simultaneous Estimation of Donepezil and Memantine by Reverse Phase HPLC in Bulk and Pharmaceutical Dosage Form. Research Journal of Pharmacy and Technology. 2012;5(7):958-61.
14.    Dhiware AD, Deshpande PB, Gandhi SV, Nair S, Vanjari S. A Simple and Sensitive RP-HPLC Method for Simultaneous Estimation of Atorvastatin Calcium, Ezetimibe and Fenofibrate in Combined Tablet Dosage Form. Research journal of pharmacy and technology. 2013;6(10):1085-8.
15.    Reddy YN, Sreeramulu J, Balaswami B. A New Stability-Indicating RP-HPLC-Pda Method for Simultaneous Estimation of Glecaprevir and Pibrentasvir in tablet dosage form. Research Journal of Pharmacy and Technology. 2019;12(2):625-31.
16.    Trefi S. Simultaneous assessment of atorvastatin-ezetimibe combination in tablets by an ion-pair RP-HPLC. Research Journal of Pharmacy and Technology. 2020;13(9):4195-9.
17.    Reddy YN, Sreeramulu J, Balaswami B. A New Stability-Indicating RP-HPLC-Pda Method for Simultaneous Estimation of Glecaprevir and Pibrentasvir in tablet dosage form. Research Journal of Pharmacy and Technology. 2019;12(2):625-31.
18.    Sravanthi T, Madhavi N. Stability Indicating UPLC Method for Simultaneous Estimation of Epalrestat and Pregabalin in Tablet Dosage Form. Research Journal of Pharmacy and Technology. 2019;12(2):489-94.
19.    Murugan S, Vetrichelvan T. UV-Spectrophotometric Absorbance Correction Methods for the Simultaneous Estimation of Tenofovir Alafenamide and Emtricitabine in Bulk and Tablet Dosage Form. Research Journal of Pharmacy and Technology. 2019;12(10):4795-8.
20.    Mahesh HR, Babu KS. A Novel Stability Indicating HPLC Assay Method for Simultaneous Estimation of Clopidogrel and Aspirin in Tablet dosage form by Using Core shell Technology column. Research Journal of Pharmacy and Technology. 2015;8(2):172-6.
21.    Tejashree RK, Dashetwar AR, Kardile DP, Jadhav AP, Bhagat VC, Shete RV. Q-absorbance ratio spectrophotometric method for the simultaneous estimation of metformin hydrochloride and voglibose in tablet dosage form. Research Journal of Pharmacy and Technology. 2021 Jun 1;14(6):3179-83.
22.    Deepthi R. A Novel UPLC Method for Simultaneous Estimation of Ertugliflozin and Sitagliptin in Bulk and Tablet Dosage Form. Research Journal of Pharmacy and Technology. 2021 Sep 14;14(9):4859-62.

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DOI: 10.5958/2231–5675 


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