Author(s): Swanand Patharkar, Kalpak Gajbhiye, Nawaz Hakam, Aman Vyawahare

Email(s): swanandrpatharkar07@gmail.com , gajbhiyekalpak@gmail.com

DOI: 10.52711/2231-5675.2022.00018   

Address: Swanand Patharkar, Kalpak Gajbhiye, Nawaz Hakam, Aman Vyawahare
Department of Quality Assurance, P.R. Pote Patil College of Pharmacy, Amravati-444604.
*Corresponding Author

Published In:   Volume - 12,      Issue - 2,     Year - 2022


ABSTRACT:
A rapid, sensitive and accurate method for Estimation of Anti- Histamine in Tablet Dosage Form by RP-HPLC. Mobile phase was Methanol: 0.1% Ortho phosphoric acid (80:20% v/v). Flow rate was 0.9 ml/min. The detection Wavelength was 227 nm. The injection volume was 20-µl. The proposed method was validated for selectivity, precision, linearity, and accuracy. All validation parameters were within the acceptable range. Linearity studies for Levamisole was performed (10-60µg/ml). The %RSD for accuracy found to be less than2%. Assay was found to be 99.17 to 101.65 respectively The range of 10-60µg /ml was selected for the linearity of a standard Levamisole. The 80%, 100% and 120% levels of recovery study were selected to perform the recovery study. Linearity studies for Levamisole was performed on (10-60µg /ml).


Cite this article:
Swanand Patharkar, Kalpak Gajbhiye, Nawaz Hakam, Aman Vyawahare. Development and Validation of New Analytical Method for Estimation of Anthelmintic in Tablet Dosage Form. Asian Journal of Pharmaceutical Analysis. 2022; 12(2):99-4. doi: 10.52711/2231-5675.2022.00018

Cite(Electronic):
Swanand Patharkar, Kalpak Gajbhiye, Nawaz Hakam, Aman Vyawahare. Development and Validation of New Analytical Method for Estimation of Anthelmintic in Tablet Dosage Form. Asian Journal of Pharmaceutical Analysis. 2022; 12(2):99-4. doi: 10.52711/2231-5675.2022.00018   Available on: https://ajpaonline.com/AbstractView.aspx?PID=2022-12-2-6


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