Vedantika Das, Ashwini Sambherao, Saroj Gajare, Amar Zalte, R. B. Saudagar
Vedantika Das1*, Ashwini Sambherao1, Saroj Gajare, Amar Zalte1, Dr. R. B. Saudagar2
1Department of Quality Assurance, Department of Pharmaceutical Chemistry, R.G. Sapkal College of Pharmacy, Anjaneri, Nasik
Volume - 6,
Issue - 3,
Year - 2016
A simple, accurate, precise, and sensitive a highly selective ultra violet spectrophotometric method has been developed for the validation and estimation in bulk and dosage form. It shows maximum absorbance 286 nm. Beer-Lambert’s was obeyed in the concentration range of in the range of 15-55µg/ml. The method was successfully validated in accordance to ICH guideline for accuracy, precision, linearity and robustness. The linear regression analysis data for calibration plots showed good linear relationship and obtain correlation factor 0.9927 for Drotaverine. Thus method was successfully applied for routine analysis of Drotaverine in bulk samples.
Cite this article:
Vedantika Das, Ashwini Sambherao, Saroj Gajare, Amar Zalte, R. B. Saudagar. UV-Spectroscopic Estimation and Validation of Drotaverine Concentration in Bulk and Dosage Form. Asian J. Pharm. Ana. 2016; 6(3): 188-190.