Author(s): Kalyani Farkade, Mukund Tawar

Email(s): kalyanifarkade01@gmail.com

DOI: 10.52711/2231-5675.2021.00034   

Address: Kalyani Farkade, Mukund Tawar
Department of Quality Assurance, P.R. Pote Patil College of Pharmacy, Amravati – 444604.
*Corresponding Author

Published In:   Volume - 11,      Issue - 3,     Year - 2021


ABSTRACT:
A Dipeptidyl peptidase-4 inhibitor teneligliptin hydrobromide is used for lowering blood glucose levels in people with diabetes mellitus. A very straight forward, quick, responsive and accurate UV- Spectrophotometric method of analysis have been developed for assessment of Teneligliptin Hydrobromide in pharmaceutical formulation. Since teneligliptin hydrobromide only absorbs UV in the low wavelength area, it cannot be identify with high sensitivity. Teneligliptin Hydrobromide has shown successful results for various analytical instruments only in the permutation of Taurine and Sodium periodate. The API was derivatives using Taurine and Sodium periodate in water and methanol. Drug exhibited distinct ?max in methanol at 281nm. Linearity was observed in the concentration range 10-80 µg/ml. The method was validated by recovery studies. The methods used are inexpensive and sensitive for the inference of teneligliptin hydrobromide in bulk drug and tablet dosage forms.


Cite this article:
Kalyani Farkade, Mukund Tawar. Analytical Method Validation and Quantitative Analysis for Active Pharmaceutical Ingredient and Marketed Formulation of Teneligliptin Hydrobromide by UV Spectroscopy. Asian Journal of Pharmaceutical Analysis. 2021; 11(3):195-8. doi: 10.52711/2231-5675.2021.00034

Cite(Electronic):
Kalyani Farkade, Mukund Tawar. Analytical Method Validation and Quantitative Analysis for Active Pharmaceutical Ingredient and Marketed Formulation of Teneligliptin Hydrobromide by UV Spectroscopy. Asian Journal of Pharmaceutical Analysis. 2021; 11(3):195-8. doi: 10.52711/2231-5675.2021.00034   Available on: https://ajpaonline.com/AbstractView.aspx?PID=2021-11-3-4


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