Author(s): Devulapally Shravya, Jorige Archana

Email(s): archanacology@gmail.com

DOI: 10.52711/2231-5675.2024.00012   

Address: Devulapally Shravya1, Jorige Archana2*
1Department of Pharmaceutical Analysis, RBVRR Women’s College of Pharmacy, Osmania University, Hyderabad, 500027, Telangana, India.
2Department of Pharmacology, RBVRR Women’s College of Pharmacy, Osmania University, Hyderabad, 500027, Telangana, India.
*Corresponding Author

Published In:   Volume - 14,      Issue - 2,     Year - 2024


ABSTRACT:
In Asia, Favipiravir, an anti- influenza medication, is widely available. Although having little proof of effectiveness, it has been widely utilised in the treatment of COVID-19. A simple UV spectroscopic method was developed for the determination of Favipiravir in pharmaceutical formulations. Favipiravir exhibited maximum absorption at 228 nm in 90% Ethanol and obeyed linearity in the concentration range of 0.5-25µg/ml. The proposed method was statistically validated. The % RSD < 2% indicates that method is precise. The % recovery results for accuracy in three levels i.e., 50%, 100% and 150% are 99.7, 99.7 and 99.8. Limits of detection and quantification were found to be 0.0435µg and 0.1318µg respectively. The ruggedness of method was studied with the help of different analyst. The robustness was performed in different 227 and 229nm. The developed UV method was validated and it was rapid, simple, sensitive and cost effective.


Cite this article:
Devulapally Shravya, Jorige Archana. A New Validated UV Spectroscopic Method for the Estimation of Favipiravir, an anti-influenza drug in COVID 19. Asian Journal of Pharmaceutical Analysis. 2024; 14(2):65-8. doi: 10.52711/2231-5675.2024.00012

Cite(Electronic):
Devulapally Shravya, Jorige Archana. A New Validated UV Spectroscopic Method for the Estimation of Favipiravir, an anti-influenza drug in COVID 19. Asian Journal of Pharmaceutical Analysis. 2024; 14(2):65-8. doi: 10.52711/2231-5675.2024.00012   Available on: https://ajpaonline.com/AbstractView.aspx?PID=2024-14-2-3


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DOI: 10.5958/2231–5675 


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