Author(s):
G. Rohit Reddy, T. Ramesh
Email(s):
rohitreddy1610@gmail.com
DOI:
10.52711/2231-5675.2023.00038 
Address:
G. Rohit Reddy*, T. Ramesh
Department of Pharmaceutical Analysis and Quality Assurance,
Vishnu Institute of Pharmaceutical Education and Research, Vishnupur, Narsapur, Medak, Telangana, India.
*Corresponding Author
Published In:
Volume - 13,
Issue - 4,
Year - 2023
ABSTRACT:
A simple, sensitive, accurate, precise and economical visible Spectrophotometric method was developed and validated for the estimation of Atorvastatin in Bulk form. The method is based on the reaction of Atorvastatin with MBTH Reagent [3-Methyl-2-Benzothiazolinone Hydrazone] in the presence of ferric chloride giving greenish blue colour chromogen which shows maximum absorbance at 566nm against reagent blank. The Chromogen obeyed Beer’s law in the concentration range of 5-25 µg/ml for Atorvastatin. The results of the analysis have been validated statistically and recovery studies confirmed the accuracy of the proposed method.
Cite this article:
G. Rohit Reddy, T. Ramesh. A New Colorimetric Development and Validation of Visible Method for Estimation of Atorvastatin in Bulk Formulation. Asian Journal of Pharmaceutical Analysis. 2023; 13(4):236-8. doi: 10.52711/2231-5675.2023.00038
Cite(Electronic):
G. Rohit Reddy, T. Ramesh. A New Colorimetric Development and Validation of Visible Method for Estimation of Atorvastatin in Bulk Formulation. Asian Journal of Pharmaceutical Analysis. 2023; 13(4):236-8. doi: 10.52711/2231-5675.2023.00038 Available on: https://ajpaonline.com/AbstractView.aspx?PID=2023-13-4-2
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