The present work describes which deals to developed and validate a simple, accurate, precise, economically effective US-VIS Spectrophotometric method for the estimation of cefprozil. These methods are developing using 280nm as the ?max of cefprozil respectively. Calibration curves were linear over the concentration ranges of 10-50µg/ml. These result demonstrate that the procedure is accurate, precise and reproducible (relatively standard deviation =1%) while being simple cheap and less time consuming and hence can be suitably applied for validation of these drug in laboratory.
Cite this article:
Thorat D.B. Methods Development and Validation of Cefprozil by UV-Vis Spectrophotometry. Asian Journal of Pharmaceutical Analysis. 2021; 11(2):70-2. doi: 10.52711/2231-5675.2021.00013
Thorat D.B. Methods Development and Validation of Cefprozil by UV-Vis Spectrophotometry. Asian Journal of Pharmaceutical Analysis. 2021; 11(2):70-2. doi: 10.52711/2231-5675.2021.00013 Available on: https://ajpaonline.com/AbstractView.aspx?PID=2021-11-2-3
1. Park TH, Kim JK, Jee JP J Pharm Biomed Anal, 2004; 36: 243-248.
2. Alarfaj NA and Abd El-Razeq J Pharm Biomed Anal; 2006, 41: 1423-1427.
3. T. H. Park, J.K. Kim, J.P. Jee, J.S.Park, C.K. Kim J. Pharm. Biomed. Anal; 2004, 36: 243-248.
4. L. Manna, L. Valvo, Chromatographia. 2004; 60: 645-649.
5. W.C. Shyu, U.A. Shukla, V.R. Shah, E.A. Papp, R.H. Barbhaiya Pharm Res.1991; 8: 1992-1996.
6. Smith, P.E. Heckelman, in: M.J. O’Neil, S. Budavari The Merck Index, 13th ed. Merck and Co Inc., White House Station, NJ, USA,. 2001.
7. The official compendia of standard USP 32, NF 27, US Pharmacopeia and National Formulary, Asian edition 2009; 1855-7.
8. Park TH, Kim JK, Jee JP J Pharm Biomed Anal; 2004; 36: 24.
9. P. Vikas, T Santosh, B. Santosh, S. Rupali, Lalit Int. J. Pharm. Pharmaceu. Sci., 2010; 2: 82
10. A.G. Elrasheed, M.M. Mohammed, E.E.I. Kamal, A.H. El-Obeid Int. J. Biomed. Sci.,2009; ; 5: 267.
11. Shukla Ravi, Patel Asha, Soni M, Modi Vishesh Jaliwala Y Asian Journal of Pharmaceutics., 2008; 9: 256.
12. Kusunoki H, Therapeutic efficacy of Acotiamide in patients with functional dyspepsia based on enhanced postprandial gastric accommodation and emptying: randomized controlled study evaluation by real-time ultrasonography. Wiley Online Library, 2012; 24(6): 540–551.
13. Matsueda K, Clinical trial: dose dependent therapeutic efficacy of Acotiamide (Z-338) in patients with functional dyspepsia – 100 mg t.i.d. is an optimal dosage. Wiley Online Library, 2010; 22(6): 618–e173.
14. Vani R, Sunitha M. Analytical method development and validation for the determination of Acotiamide hydrochloride using reverse phase HPLC method in bulk and tablet dosage form. World journal of pharmacy and pharmaceutical sciences. 2010; 6(10): 768-775.
15. Jing LI, Huang R, Zhi W, Haijun QU, Meijuan S, Zhao Z. Development and Validation of a Sensitive and Specific LC–MS-MS Method for the Determination of Acotiamide in Rat Plasma. Journal of Chromatographic Science. 2016; 54(6): 1004–1009.
16. Patel PN, Kalariya PD, Swamy CV, Gananadhamu S, Srinivas R. Quantitation of Acotiamide in rat plasma by UHPLC-Q-TOF-MS: method development, validation and application to pharmacokinetics. Biomed Chromatography. 2016; 30(3): 363-368.
17. Thummar M, Patel PN, Samanthula G, Ragampeta S. Stability-indicating assay method for Acotiamide: Separation, identification and characterization of its hydroxylated and hydrolytic degradation products along with a process-related impurity by ultra-high-performance liquid chromatography/electrospray ionization quadrupole time-of-flight tandem mass spectrometry. Wiley Online Library, 2017; 31(21): 1813–1824.
18. ICH Q2 (R1) validation of analytical procedures: text and methodology, International Conference on Harmonization, Nov, 1996.