Author(s): Jumle R. S.*, Mundhey A.S., Wate S.P., Dangare S.S., Ramteke U.D.

Email(s): rjumle2010@gmail.com

DOI: Not Available

Address: Jumle R. S.*, Mundhey A.S., Wate S.P., Dangare S.S., Ramteke U.D.
Department of Pharmaceutical Chemistry, Sharad Pawar College of Pharmacy Nagpur, India
*Corresponding Author

Published In:   Volume - 2,      Issue - 4,     Year - 2012


ABSTRACT:
The present study deals with UV spectrophotometric method development and validation for estimation of Tizanidine and Aceclofenac tablet dosage form by Viedort’s method and first order UV derivative spectrophotometry. The Vierodt's method involves measurement of absorbance at ?max of Tizaridine and Aceclofenac at 282 nm respectively. The linearity of Tizanidine and Aceclofenac was found to be in the range of 1-10 µg/ml respectively. The % recovery of Tizanidine and Aceclofenac was found out to be 99.2% and 99.69%s respectively. First order CV derivative spectrophotonmetry (D1 method). the zero crossing method was chosen as Tizanidine could he easily analyzed without any interference from Aceclofenac and vice-versa. Tizanidine was determined by measurement of its D1 amplitude at the zero crossing point of Aceclofenac at (270nm), While Aceclofenac was determined by measurement of its D1 amplitude at zero crossing point of Tizanidine at (318 nm) The proposed method was validated as per ICH guidelines.


Cite this article:
UV- Spectrophotometric Method Development and Validation for Estimation of Tizanidine and ceclofenac in Tablet Formulation. Asian J. Pharm. Ana. 2(4): Oct. - Dec. 2012; Page 101-103.

Cite(Electronic):
UV- Spectrophotometric Method Development and Validation for Estimation of Tizanidine and ceclofenac in Tablet Formulation. Asian J. Pharm. Ana. 2(4): Oct. - Dec. 2012; Page 101-103.   Available on: https://ajpaonline.com/AbstractView.aspx?PID=2012-2-4-1


Recomonded Articles:

Author(s): K. Pramod, Shahid H. Ansari, Javed Ali

DOI:         Access: Open Access Read More

Author(s): G. Krishnamoorthy, C. Diana Priyadarshini, R. Senthamarai

DOI:         Access: Open Access Read More

Author(s): Shobha Rani G, Lohita M, Jaya Preethi P, Madhavi R, Sunisitha B, Mounika D

DOI:         Access: Open Access Read More

Author(s): Sushil D. Patil, Sayali K. Chaure, Maswood Ahmed Hafizur Rahman, Prajkta U. Varpe, Sanjay Kshirsagar.

DOI: 10.5958/2231-5675.2017.00004.7         Access: Open Access Read More

Author(s): S. Subramanya Raj Urs, Bindu M., Ramyashree D., Sowmya K. N.

DOI: 10.5958/2231-5675.2020.00034.4         Access: Open Access Read More

Author(s): Yogita R. Indalkar, Aloorkar N.H.

DOI: 10.5958/2231-5675.2015.00028.9         Access: Open Access Read More

Author(s): Saroj Kumar Raul, Gopal Krishna Padhy, Pramudula Ramya Krishna, Boddu Uma Madhu Priya

DOI:         Access: Open Access Read More

Author(s): Santosh Gada, Anand Kumar Y, Saritha, C. Mallikarjuna Setty

DOI: 10.5958/2231-5675.2018.00036.4         Access: Open Access Read More

Author(s): Mansi J. Chaudhari, Suraj R. Chaudhari, Shailesh S. Chalikwar, Atul A. Shirkhedkar

DOI: 10.5958/2231-5675.2018.00008.X         Access: Open Access Read More

Author(s): Saroj Kumar Raul, Bukkuru Spandana, Patibandla Sameera, Vegiraju Vikitha

DOI:         Access: Open Access Read More

Author(s): Paras Virani, Rajanit Sojitra, Hasumati Raj, Vineet Jain

DOI: 10.5958/2231-5675.2015.00025.3         Access: Open Access Read More

Author(s): Santosh S. Chhajed a, Sandeep S. Sonawane, Akshada P. Pingle, Neelam Dashputre, Sakshi, Sanjay J. Kshirsagara

DOI: 10.5958/2231-5675.2019.00005.X         Access: Open Access Read More

Author(s): Ramesh L Sawant, Rahul B Kale, Amol S Ghodechor, Abhijit B Sherkar, Kunal R Sanklecha

DOI: 10.5958/2231-5675.2017.00025.4         Access: Open Access Read More

Asian Journal of Pharmaceutical Analysis (AJPA) is an international, peer-reviewed journal, devoted to pharmaceutical analysis...... Read more >>>

RNI: Not Available                     
DOI: 10.5958/2231–5675 


Recent Articles




Tags