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Asian Journal of Pharmaceutical Analysis
ISSN: 2231-5675(Online), 2231-5667(Print)
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Colorimetric Estimation of Secnidazole in Bulk and Tablet Dosage Form
J. Anu Deepa
R. Siva Kumar
R. Venkata Narayanan
J. Anu Deepa*, N. Santhi, R. Ramya, R. Siva Kumar, R. Venkata Narayanan.
R.V.S College of Pharmaceutical Sciences, Sulur, Coimbatore – 641 402.
A new simple, sensitive and precise visible spectrophotometric method has been developed for the determination of Secnidazole in bulk and in pharmaceutical formulation. This method is based on the reduction of secnidazole, in the presence of 4N Hydrochloric acid and ethanol to form yellow colored chromogen. Which was estimated at an absorption maximum of 477.5nm .This method has the linearity in the concentration range of 100-500µg/ml. This method is statistically evaluated for efficacy.
Secnidazole, Reduction method.
J. Anu Deepa, N. Santhi, R. Ramya, R. Siva Kumar, R. Venkata Narayanan. Colorimetric Estimation of Secnidazole in Bulk and Tablet Dosage Form. Asian J. Pharm. Ana. 2(1): Jan.-Mar. 2012; Page 20-21.
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