Volume No. :   10

Issue No. :  2

Year :  2020

ISSN Print :  2231-5667

ISSN Online :  2231-5675


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In-Vitro Evaluation of different marketed brands of Rabiprazol Tablets using Quality Control Tests



Address:   Mayur N. Ghotkar*, Rohit M. Jamdar, Rohit R. Mahajan, Ashwinkumar S. Chougule, Sneha M. Dhavane, Pooja N. Ingole, Ganesh B. Vambhurkar
Rajarambapu College of Pharmacy, Kasegaon, Dist-Sangli, Maharashtra, India-415404.
*Corresponding Author
DOI No: 10.5958/2231-5675.2020.00017.4

ABSTRACT:
A lot of suppliers sale the rabiprazol tablets as the OTC product among the patients, as a mostly use to treat certain stomach and esophagus problems (such as acid reflux, ulcers). Ultimate aim of this research was to compare and evaluate different brands of rabiprazol tablets for their performance which are sold in sangli district. Five different brands of the rabriprazol sodium tablets (rabiprazol tablets) were randomly collected from the different pharmacy shops present in the sangli district. To perform this experimental work various official books like USP and BP was used to determine the in vitro quality tests using various procedure as well as different analytical tests. In evaluation of different brands of rabiprazol tablets we were perform determination of different parameters like weight variation, friability, hardness, drug content, identification test, disintegration time and dissolution profile. By performing weight variation and friability test we were fond that different brands show acceptable value. From UV analysis of different sample we were found that none of the brand contain NLT 95 % of active drug content. Each and every branded tablet taken for comparative evaluation gives different results from each other but no one crosses the limits given in official books.
KEYWORDS:
Rabiprazol, Comparative evaluation, Quality control test, Different brands of rabiprazol.
Cite:
Mayur N. Ghotkar, Rohit M. Jamdar, Rohit R. Mahajan, Ashwinkumar S. Chougule, Sneha M. Dhavane, Pooja N. Ingole, Ganesh B. Vambhurkar. In-Vitro Evaluation of different marketed brands of Rabiprazol Tablets using Quality Control Tests. Asian J. Pharm. Ana. 2020; 10(2): 99-102.
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