Registered User Login
Asian Journal of Pharmaceutical Analysis
ISSN: 2231-5675(Online), 2231-5667(Print)
News & Conferences
Volume No. :
Issue No. :
ISSN Print :
ISSN Online :
Click to Login
Development and Validation of Visible Method for Estimation of Cilazapril in Bulk Formulation by MBTH Reagent
G. Rohit Reddy
VVS. Rajendra Prasad
Chavi Dagar, G. Rohit Reddy*, VVS. Rajendra Prasad
Department of Pharmaceutical Analysis and Quality Assurance, Vishnu Institute of Pharmaceutical Education and Research, Vishnupur, Narsapur, Medak, Telangana, India.
A simple, sensitive, accurate, precise and economical visible Spectrophotometric method was developed and validated for the estimation of Cilazapril in Bulk form. The method is based on the reaction of Cilazapril with MBTH Reagent [3-Methyl-2-Benzothiazolinone Hydrazone] in the presence of Ferric chloride producing greenish yellow colour chromogen which shows maximum absorbance at 402nm against reagent blank. The Chromogen obeyed Beer’s law in the concentration range of 10-50 µg/ml for Cilazapril. The results of the analysis have been validated statistically and recovery studies.
Cilazapril, MBTH Reagent, Ferric chloride, Visible Spectrophotometric.
Chavi Dagar, G. Rohit Reddy, VVS. Rajendra Prasad. Development and Validation of Visible Method for Estimation of Cilazapril in Bulk Formulation by MBTH Reagent. Asian J. Pharm. Ana. 2017; 7(1): 15-17.
Visitor's No. :