Volume No. :   5

Issue No. :  1

Year :  2015

ISSN Print :  2231-5667

ISSN Online :  2231-5675


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Isoniazid: A Review of Analytical Methods



Address:   Madhavi R.*, Mohana Krishna A., Shobha Rani G., Mounika D.
Department of Pharmaceutical Analysis, Sree Vidyanikethan College of Pharmacy, Sree Sainath Nagar, Rangampet, Tirupati-517501, Chittoor Dist, Andhra Pradesh, India.
*Corresponding Author
DOI No: 10.5958/2231-5675.2015.00008.3

ABSTRACT:
Isoniazid is an anti –tubercular drug, which is mostly used in the treatment and prevention of tuberculosis. It acts by inhibiting the synthesis of mycolic acid, required for mycobacterial cell wall synthesis in mycobacterium(M) tuberculosis. This article examines published analytical techniques that are reported so far for the determination of isoniazid in bulk, pharmaceutical formulation and biological samples. They include various techniques like spectrophotometry, electrochemical methods, capillary electrophoresis, high performance liquid chromatography, high performance thin layer chromatography, capillary gas chromatography and liquid chromatography-mass spectrophotometry.
KEYWORDS:
Isoniazid, Analytical methods, Tuberculosis, Mycolic acid
Cite:
Madhavi R., Mohana Krishna A., Shobha Rani G., Mounika D. Isoniazid: A Review of Analytical Methods. Asian J. Pharm. Ana. 5(1): Jan.- March 2014; Page 41-45.
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