Volume No. :   4

Issue No. :  4

Year :  2014

ISSN Print :  2231-5667

ISSN Online :  2231-5675


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Glimepiride: A Review of Analytical Methods



Address:   Shobha Rani G*, Lohita M, Jaya Preethi P, Madhavi R, Sunisitha B, Mounika D
Sree Vidyanikethan College of Pharmacy, Sree Sainath Nagar, Tirupati-517 102, Andhra Pradesh, India.
*Corresponding Author
DOI No:

ABSTRACT:
Glimepiride is an oral anti-diabetic drug, which is mostly used in the treatment of Type 2 diabetes mellitus. It acts by stimulating insulin secretions from the beta cells of pancreas and is also known to enhance the peripheral insulin sensitivity thereby decreasing insulin resistance. This article examines published analytical methods that are reported so far for the determination of glimepiride in pharmaceutical formulations and biological samples. They include various techniques like spectrophotometry, electrochemical methods, capillary electrophoresis, high-performance liquid chromatography, micellarelectro kinetic capillary chromatography(MECC) with diode-array detection (DAD), liquid chromatography-electrospray ionization-tandem mass spectroscopy (LC-ESI-MS), liquid chromatography-mass spectroscopy (LC-MS) and thin layer chromatography (TLC).
KEYWORDS:
Glimepiride, Analytical methods, Type 2 diabetes mellitus
Cite:
Shobha Rani G, Lohita M, Jaya Preethi P, Madhavi R, Sunisitha B, Mounika D. Glimepiride: A Review of Analytical Methods. Asian J. Pharm. Ana. 4(4): Oct. - Dec. 2014; Page 178-182.
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