Volume No. :   3

Issue No. :  2

Year :  2013

ISSN Print :  2231-5667

ISSN Online :  2231-5675


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Development and validation of UV spectrophotometric method for the quantitative estimation of eugenol



Address:   K. Pramod1, Shahid H. Ansari2, Javed Ali1*
1Department of Pharmaceutics, Faculty of Pharmacy, Jamia Hamdard, Hamdard Nagar, New Delhi – 110062, India.
2Department of Pharmacognosy & Phytochemistry, Faculty of Pharmacy, Jamia Hamdard, Hamdard Nagar, New Delhi – 110062, India.
*Corresponding Author
DOI No:

ABSTRACT:
Eugenol is an allyl chain-substituted guaiacol and finds variety of applications. Thus development of a validated UV spectrophotometric method will always be advantageous as the method is simple and rapid. The method was validated according to International Conference on Harmonisation (ICH) guidelines Q2(R1) with respect to linearity and range, precision, accuracy, detection limit (DL) and quantitation limit (QL). The detection limit (DL) and quantitation limit (QL) were determined as per the ICH guidelines and were found to be 0.82 and 2.48 µg mL-1 respectively. The method is expected to be useful in a variety of industries where eugenol finds its application.
KEYWORDS:
ICH, linearity, range, precision, accuracy, detection limit, quantitation limit
Cite:
K. Pramod, Shahid H. Ansari, Javed Ali. Development and validation of UV spectrophotometric method for the quantitative estimation of eugenol. Asian J. Pharm. Ana. 3(2): April- June 2013; Page 58-61.
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