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Asian Journal of Pharmaceutical Analysis
ISSN: 2231-5675(Online), 2231-5667(Print)
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Novel Colorimetric Methods for quantitative estimation of Diacerin from capsule Formulation.
Sanjay Bais1*, Indrajeet Singhvi2, Anil Chandewar3 Mrunal Shirsat2
1Research Scholar, PRIST University, Thanjavur, Tamilnadu
2Pacific College of Pharmacy, Debari, Udaipur (Rajasthan) 313003
3P.Wadhwani College of Pharmacy, Yavatmal, Maharahtra
Two simple and sensitive colorimetric methods have been developed for the quantitative estimation of Diacerin from Pharmaceutical Capsule dosage form. Developed methods are based on the formation of chloroform extractable ion pair coloured complex of drug with Orange II (Method A) and Tropoelin (Method B). The complex formed in method A and B showed maximum absorbance at 435. Linearity was obeyed in concentration range of 50-350 µgm/ml and 50-250 µgm/ml of Diacerin for method A and B respectively. The results of analysis were validated statistically and by recovery studies.
Diacerin, Orange II, Tropoelin, Colorimetric method
Sanjay Bais, Indrajeet Singhvi, Anil Chandewar, Mrunal Shirsat. Novel Colorimetric Methods for quantitative estimation of Diacerin from capsule Formulation. Asian J. Pharm. Ana. 3(2): April- June 2013; Page 44-47.
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