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Asian Journal of Pharmaceutical Analysis
ISSN: 2231-5675(Online), 2231-5667(Print)
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A New Analytical Method Development and Validation for Estimation of Ciprofloxacin in Bulk and Pharmaceutical Dosage Form
Sravan Prasad Macherla
Praveena Kumari Matta
Madhu Chandaka S.
Manoranjan Sabat*1, Sharada Nalla1, Venkateswarlu Goli1, Sravan Prasad Macherla2, Praveena Kumari Matta2, Madhu Chandaka S.2
1Venkateswara Institute of Pharmaceutical Seinces, Cherlapally, Nalgonda -508001.
2Sri Indu Institute of Pharmacy, Sheriguda, Ibrahimpatnam, R.R Dist. -501510
A sensitive, precise, accurate and simple UV spectrophotometric method has been developed for estimation of ciprofloxacin in bulk and pharmaceutical dosage form. The drug shows maximum absorbance at 273 nm (?max). The linearity was observed in the concentration range of 5-50mcg/ml. The proposed method has been applied successfully to the analysis of cited drug in pharmaceutical formulation. Recovery study was performed to confirm the accuracy of the method. The method was validated as per ICH guide lines.
Estimation, Ciprofloxacin, UV Spectrophotometer.
Manoranjan Sabat, Sharada Nalla, Venkateswarlu Goli, Sravan Prasad Macherla, Praveena Kumari Matta, Madhu Chandaka S.. A New Analytical Method Development and Validation for Estimation of Ciprofloxacin in Bulk and Pharmaceutical Dosage Form. Asian J. Pharm. Ana. 2(4): Oct. - Dec. 2012; Page 116-117.
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