Volume No. :   1

Issue No. :  2

Year :  2011

ISSN Print :  2231-5667

ISSN Online :  2231-5675


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Target Discovery and Validation: Advances in Molecular Pharmacology



Address:   Dibyajyoti Saha*1, Mayukh Jana2 Supradip Mandal2
1School of Pharmacy, Chouksey Engineering College, Lal Khadan, Masturi Road, Bilaspur-495004,C.G.
2Bharat Technology, Banitabla, Uluberia, Howrah-711316
*Corresponding Author
DOI No:

ABSTRACT:
The molecular pharmacology involving aspects of biological, medical and pharmaceutical sciences. It is concerned with invention, discovery, design, identification and preparation of biologically active compounds, the study of their metabolism, the interpretation of their mode of action at the molecular level. The physiology based drug discovery follows physiological readouts and by contrast, the road of target based drugs discovery begins with identifying the function of a possible therapeutic target and its role in disease. The validation of a molecular target in vitro usually proceeds the validation of a therapeutic concept in vivo; together this defines its clinical potential. The present article gives disease mechanisms of target discovery and outline of target validation with its pathways.
KEYWORDS:
Target discovery, Target validation, Molecular target, Disease genes, Molecular pharmacology.
Cite:
Dibyajyoti Saha, Mayukh Jana, Supradip Mandal. Target Discovery and Validation: Advances in Molecular Pharmacology. Asian J. Pharm. Ana. 1(2): April-June 2011; Page 27-28.
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