Volume No. :   1

Issue No. :  1

Year :  2011

ISSN Print :  2231-5667

ISSN Online :  2231-5675


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Spectrophotometric Estimation of Ziprasidone in Bulk and In Pharmaceutical Formulations



Address:   *N. Santhi Ch. Deepthi, S.S. Rajendran, S. Gananadhamu, G. Devala Rao and Sai Lohit
K.V.S.R. Siddhartha College of Pharmaceutical Sciences, Vijayawada
*Corresponding Author
DOI No:

ABSTRACT:
A new simple, sensitive and precise visible spectrophotometric method has been developed for the determination of ziprasidone in bulk and in pharmaceutical formulations. This method is based on the hydrolysis of Ziprasidone, followed by diazotization and coupling with N-(1-naphthyl) ethylene diamine dihydrochloride to form an azo dye which was estimated at an absorption maximum of 540nm (pink color). This method has the linearity in the concentration range of 2-10µg/ml. This method is statistically evaluated for efficacy.
KEYWORDS:
Spectrophotometric Estimation of Ziprasidone in Bulk and In Pharmaceutical Formulations
Cite:
N. Santhi Ch. Deepthi, S.S. Rajendran, S. Gananadhamu, G. Devala Rao , Sai Lohit. Spectrophotometric Estimation of Ziprasidone in Bulk and In Pharmaceutical Formulations. Asian J. Pharm. Ana. 1(1): Jan.-Mar. 2011; Page 08-09.
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